Roussel B, Birembaut P, Lévy M, Dropsy G, Fandre M
Helv Paediatr Acta. 1979 Feb;34(1):93-8.
The authors describe a case of congenital syphilitic nephropathy in an infant. The review of the reports in the literature shows many similarities of this congenital disease with the syphilitic nephrotic syndrome in the adult. The prognosis is favorable provided the diagnosis is made sufficiently early. Histological studies utilizing light-, electron- and immunofluorescence-microscopy gave results consistent with extramembranous glomerulonephritis with possible evolution towards endo- and extracapillary proliferative glomerulonephritis. This is one of the rare renal diseases with a known antigen.
作者描述了一例婴儿先天性梅毒肾病的病例。对文献报道的回顾显示,这种先天性疾病与成人梅毒肾病综合征有许多相似之处。如果诊断足够早,预后良好。利用光镜、电镜和免疫荧光显微镜进行的组织学研究结果与膜外肾小球肾炎一致,可能会发展为毛细血管内和毛细血管外增生性肾小球肾炎。这是一种罕见的具有已知抗原的肾脏疾病。