Flewett T H, Parker R G, Philip W M
J Clin Pathol. 1969 Jan;22(1):60-6. doi: 10.1136/jcp.22.1.60.
A case is described of herpetic hepatitis in a pregnant woman with primary herpetic stomatitis. Intranuclear inclusion bodies and virus particles were found in hepatocytes, and herpes virus was isolated from a liver biopsy and from oral swabs but not from blood. From rising titres of neutralizing and complement-fixing antibody it is concluded that the oral infection was a primary one. Factors predisposing to the hepatitis are discussed.
本文描述了一例患有原发性疱疹性口炎的孕妇发生疱疹性肝炎的病例。在肝细胞中发现了核内包涵体和病毒颗粒,从肝活检组织和口腔拭子中分离出疱疹病毒,但血液中未分离出。根据中和抗体和补体结合抗体滴度的升高,得出口腔感染是原发性感染的结论。文中讨论了易引发肝炎的因素。