Lawley T J, Hertz K C, Wade T R, Ackerman A B, Katz S I
JAMA. 1979 Apr 20;241(16):1696-9.
We report an intensely pruritic cutaneous eruption that occurs in the third trimester of pregnancy. The clinical manifestations include erythematous urticarial papules and plaques that begin on the abdomen and spread to involve the thighs and occasionally the buttocks and arms. This dermatosis appears to be clinically distinct from previously described pruritic eruptions occurring in pregnancy. Biopsy specimens of the lesions show two histological patterns. We propose that this entity be termed "pruritic urticarial papules and plaques of pregnancy (PUPPP)".
我们报告了一种发生在妊娠晚期的剧烈瘙痒性皮肤疹。临床表现包括腹部开始出现的红斑性荨麻疹丘疹和斑块，并蔓延至大腿，偶尔累及臀部和手臂。这种皮肤病在临床上似乎与先前描述的妊娠瘙痒性皮疹不同。病变的活检标本显示出两种组织学模式。我们建议将这种病症称为“妊娠瘙痒性荨麻疹丘疹和斑块（PUPPP）”。
