Pyrophosphate, phosphonates and pyrophosphatases in the regulation of calcification and calcium homeostasis.
作者信息
Russell R G, Fleisch H
出版信息
Proc R Soc Med. 1970 Sep;63(9):876. doi: 10.1177/003591577006300906.
Abstract
摘要
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EXCRETION OF INORGANIC PYROPHOSPHATE IN HYPOPHOSPHATASIA.
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Isolation from urine of pyrophosphate, a calcification inhibitor.
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Association of inorganic pyrophosphatase activity with normal calcification of rat costal cartilage in vivo.
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Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo.
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Partial purification and some properties of human bone alkaline phosphatase.
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Pyrophosphate and diphosphonates in calcium metabolism and their possible role in renal failure.
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Effect of pyrophosphate on hydroxyapatite and its implications in calcium homeostasis.
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