McSwiggan D A, George R
Bull World Health Organ. 1970;43(2):295-300.
Several studies have been reported on the comparative susceptibility of various cell cultures for the primary isolation of enteric viruses. The present report gives a comparison of human embryo kidney cells and rhesus monkey kidney cells for the primary isolation of viruses from faecal specimens. Altogether, 148 enteroviruses, covering 21 serotypes, and 20 adenoviruses were isolated. The marked sensitivity of human embryo kidney cells to adenoviruses was again demonstrated. These cells, however, were found to be significantly less sensitive than rhesus monkey cells for the isolation of the enteroviruses encountered. This finding is in conflict with the results of a previous study and is partly explained by the difference in enterovirus composition of the two series. The value of human embryo kidney cells for the primary isolation of enteric viruses would seem to be closely related to the prevalence of adenoviruses and certain coxsackievirus A serotypes in the population studied.
已有多项关于各种细胞培养物对肠道病毒进行初次分离的比较敏感性的研究报告。本报告对人胚肾细胞和恒河猴肾细胞从粪便标本中初次分离病毒进行了比较。总共分离出148株肠道病毒，涵盖21个血清型，以及20株腺病毒。再次证明了人胚肾细胞对腺病毒具有显著敏感性。然而，发现这些细胞在分离所遇到的肠道病毒方面比恒河猴细胞的敏感性显著更低。这一发现与先前一项研究的结果相矛盾，部分原因是两个系列肠道病毒组成的差异。人胚肾细胞在肠道病毒初次分离中的价值似乎与所研究人群中腺病毒和某些柯萨奇病毒A血清型的流行率密切相关。
