Storgaard L, Bischoff N, Henriksen F W, Fischerman K, Jarnum S
Scand J Gastroenterol. 1979;14(2):225-30. doi: 10.3109/00365527909179874.
The survival rate in 709 patients with chronic inflammatory bowel disease (CIBD) was calculated by the log rank test. There were 297 patients with Crohn's disease (CD) and 412 patients with ulcerative colitis (UC). In both diseases there was a survival rate of about 94% in the first year of observation against an expected rate of 99.5% in a general population matched for sex and age. This was because a large number of patients were severely ill at their first admission and required immediate or early surgery. During the subsequent 11 years the death rate in CIBD was higher (two to three times) than in the general population. After 12 years the survival rate was about 77% in both CD and UC. The difference was statistically insignificant. There was no significant difference in the sex ratio. The cancer rate was low. No gastrointestinal cancer occurred among patients with CD. Colorectal cancer was found in four patients with UC, three of whom presented with cancer on their first admission. It is concluded that recurrence and reoperation for recurrence in Crohn's disease have not impaired the prognosis compared to ulcerative colitis in this series.
通过对数秩检验计算了709例慢性炎症性肠病（CIBD）患者的生存率。其中有297例克罗恩病（CD）患者和412例溃疡性结肠炎（UC）患者。在这两种疾病中，观察的第一年生存率约为94%，而在性别和年龄匹配的普通人群中预期生存率为99.5%。这是因为大量患者首次入院时病情严重，需要立即或早期手术。在随后的11年中，CIBD的死亡率高于普通人群（两到三倍）。12年后，CD和UC的生存率均约为77%。差异无统计学意义。性别比例无显著差异。癌症发生率较低。CD患者中未发生胃肠道癌症。4例UC患者发现结直肠癌，其中3例首次入院时即患有癌症。结论是，在本系列中，与溃疡性结肠炎相比，克罗恩病的复发及复发后的再次手术并未损害预后。
