McDonald J T, Margen S
Am J Clin Nutr. 1979 Apr;32(4):817-22. doi: 10.1093/ajcn/32.4.817.
Six healthy males were studied under metabolic unit conditions to determine the effects of wine vs ethanol on the absorption of various elements. Fluid, sodium, and potassium data are reported here. The following test beverages in the amount of 1 liter/day were administered in random order to each of the subjects during four 18-day experimental periods: Zinfandel wine (9.3% w/v alcohol); dealcoholized Zinfandel wine; pure ethanol (9.3% w/v aqueous alcohol solution); and deionized water. A strictly controlled isocaloric formula diet was given with the test beverage in four equal feedings over a 12-hr period. No diuretic effect of alcohol was detected in any of the subjects. Urinary sodium was significantly less during the dealcoholized wine period than during the ethanol and water periods. Urinary potassium was significantly greater during ethanol administration as compared with the other test beverages. Fecal and serum sodium and potassium were essentially unchanged throughout the study.
六名健康男性在代谢单元条件下接受研究，以确定葡萄酒与乙醇对各种元素吸收的影响。本文报告了液体、钠和钾的数据。在四个为期18天的实验期间，以每天1升的量，将以下测试饮料按随机顺序给予每名受试者：仙粉黛葡萄酒（酒精含量9.3%，重量/体积）；脱醇仙粉黛葡萄酒；纯乙醇（酒精含量9.3%，水醇溶液）；以及去离子水。在12小时内分四次等量喂食，将严格控制的等热量配方饮食与测试饮料一起给予。在任何受试者中均未检测到酒精的利尿作用。脱醇葡萄酒期间的尿钠显著低于乙醇和水期间。与其他测试饮料相比，乙醇给药期间的尿钾显著更高。在整个研究过程中，粪便和血清中的钠和钾基本没有变化。
