Flynn M A, Nolph G B, Flynn T C, Kahrs R, Krause G
Am J Clin Nutr. 1979 May;32(5):1051-7. doi: 10.1093/ajcn/32.5.1051.
One hundred sixteen male volunteers between the ages of 32 and 62 years (mean age 46) consumed two whole fresh eggs daily in their customary diets for 3 months and also eliminated eggs for 3 months before or after eating eggs. The men had had normal-range serum cholesterol and triglycerides for the past 7 years. Four-day food records kept by them in each experimental period were assessed for nutrient intake. A Latin square design allowed analyses for season and sequential effects on serum lipids. The serum cholesterol and triglyceride levels at the end of 6 months were compared with their initial levels on customary free choice diets as well as their levels after the first 3 months of study. No significant increase in mean serum cholesterol was found nor was there a significant association of dietary cholesterol intake with either serum cholesterol or triglyceride.
116名年龄在32至62岁之间（平均年龄46岁）的男性志愿者，在其日常饮食中每天食用两个完整的新鲜鸡蛋，持续3个月，并且在食用鸡蛋之前或之后3个月不食用鸡蛋。这些男性在过去7年中血清胆固醇和甘油三酯水平处于正常范围。对他们在每个实验阶段记录的4天食物摄入量进行营养评估。采用拉丁方设计来分析季节和连续因素对血脂的影响。将6个月末的血清胆固醇和甘油三酯水平与其在习惯自由选择饮食时的初始水平以及研究前3个月后的水平进行比较。未发现平均血清胆固醇有显著升高，饮食胆固醇摄入量与血清胆固醇或甘油三酯之间也没有显著关联。
