Faculty of Health and Social Services, Kanagawa University of Human Services, Yokosuka 238-8550, Japan.
Faculty of Core Research, Ochanomizu University, Tokyo 112-8610, Japan.
Int J Environ Res Public Health. 2023 Feb 25;20(5):4138. doi: 10.3390/ijerph20054138.
The relationship between egg consumption and ischemic heart disease (IHD) remains controversial as there is still no clear answer regarding the relationship, with research limited to a few geographical regions. In the current study, we conducted a longitudinal analysis of the association between egg intake and IHD incidence (IHDi) and mortality (IHDd) using 28 years of international data from 1990 to 2018. Egg intake (g/day/capita) by country was obtained from the Global Dietary Database. Age-standard IHDi and IHDd rates per 100,000 subjects in each country were obtained from the 2019 Global Burden of Disease database. The analysis included a total of 142 countries with populations of at least one million, for which all data were available from 1990 to 2018. Eggs are consumed worldwide, and regional differences in consumption are also shown. Utilizing IHDi and IHDd as objective variables and egg intake as an explanatory variable, the analysis was conducted using linear mixed models, which controlled for inter- and intra-country variation from year to year. The results showed a significant negative association between egg intake, and IHDi (-0.253 ± 0.117, < 0.05) and IHDd (-0.359 ± 0.137, < 0.05). The analysis was carried out using R 4.0.5. The results suggest that adequate egg intake might suppress IHDi and IHDd on a global scale.
鸡蛋摄入量与缺血性心脏病（IHD）之间的关系仍然存在争议，因为目前仍不清楚两者之间的关系，相关研究仅限于少数地理区域。在本研究中，我们利用 1990 年至 2018 年来自全球 142 个国家/地区的 28 年国际数据，对鸡蛋摄入量与 IHD 发病率（IHDi）和死亡率（IHDd）之间的关系进行了纵向分析。通过全球膳食数据库获取各国的鸡蛋摄入量（g/人/天/ capita）。通过 2019 年全球疾病负担数据库获取各国每 10 万人的年龄标准化 IHDi 和 IHDd 率。该分析纳入了人口至少为 100 万的 142 个国家，这些国家在 1990 年至 2018 年期间都有所有数据。鸡蛋在全球范围内被消费，且存在地区消费差异。本研究使用线性混合模型作为分析方法，以 IHDi 和 IHDd 为因变量，以鸡蛋摄入量为自变量，该模型控制了年际间的国家间和国家内的差异。结果表明，鸡蛋摄入量与 IHDi（-0.253 ± 0.117， < 0.05）和 IHDd（-0.359 ± 0.137， < 0.05）呈显著负相关。本研究使用 R 4.0.5 进行分析。结果表明，在全球范围内，适量摄入鸡蛋可能会抑制 IHDi 和 IHDd。
