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同源和异源病毒的感染性及转录酶活性重建:水疱性口炎病毒(印第安纳血清型)、钱德布尔病毒、水疱性口炎病毒(新泽西血清型)及科卡尔病毒

Reconstitution of infectivity and transcriptase activity of homologous and heterologous viruses: vesicular stomatitis (Indiana serotype), Chandipura, vesicular stomatitis (New Jersey serotype), and Cocal viruses.

作者信息

Bishop D H, Emerson S U, Flamand A

出版信息

J Virol. 1974 Jul;14(1):139-44. doi: 10.1128/JVI.14.1.139-144.1974.

Abstract

RNA TRANSCRIPTASE ACTIVITIES HAVE BEEN RECONSTITUTED FROM FRACTIONATED COMPONENTS OF FOUR RHABDOVIRUSES

vesicular stomatitis virus (VSV) (Indiana serotype), Cocal, VSV (New Jersey), and Chandipura viruses. Heterologous reconstitution of transcription has been observed between template and enzyme fractions of VSV Indiana and Cocal viruses but not to any significant extent between components of the other two viruses with VSV Indiana template or enzyme. Homologous reconstitution of infectivity has been obtained for each virus from their respective parts as well as heterologous reconstitution between Cocal and VSV Indiana components.

摘要

已从四种弹状病毒的分级组分中重组出RNA转录酶活性:水疱性口炎病毒(VSV)(印第安纳血清型)、科卡尔病毒、VSV(新泽西)和钱迪普拉病毒。已观察到VSV印第安纳病毒和科卡尔病毒的模板与酶组分之间存在转录的异源重组,但在其他两种病毒的组分与VSV印第安纳模板或酶之间未观察到显著的异源重组。已从各自的部分获得了每种病毒的感染性同源重组,以及科卡尔病毒和VSV印第安纳组分之间的异源重组。

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