Uno I, Ishikawa T
J Bacteriol. 1973 Mar;113(3):1249-55. doi: 10.1128/jb.113.3.1249-1255.1973.
The adenyl cyclase and phosphodiesterase metabolizing adenosine 3',5'-cyclic monophosphate (cyclic AMP) were detected in mycelia of strains of Coprinus macrorhizus which form fruiting bodies, but not in those of strains which do not form fruiting bodies. The adenyl cyclase synthesized cyclic AMP from adenosine triphosphate. The phosphodiesterase degr[UNK]ded cyclic AMP to adenosine-5'-monophosphate and was inhibited by adenosine-3'-monophosphate, theophylline, and caffeine. The strains which form fruiting bodies incorporated and metabolized cyclic AMP, but strains which do not form fruiting bodies did not. The possible participation of cyclic AMP in the induction of fruiting bodies is discussed.
在能形成子实体的大根鬼伞菌株的菌丝体中检测到了代谢3',5'-环磷酸腺苷(环磷腺苷)的腺苷酸环化酶和磷酸二酯酶,而在不能形成子实体的菌株中未检测到。腺苷酸环化酶由三磷酸腺苷合成环磷腺苷。磷酸二酯酶将环磷腺苷降解为5'-单磷酸腺苷,并受到3'-单磷酸腺苷、茶碱和咖啡因的抑制。能形成子实体的菌株摄取并代谢环磷腺苷,而不能形成子实体的菌株则不能。本文讨论了环磷腺苷在子实体诱导过程中可能的参与情况。