Morhenn V, Rabinowitz Z, Tomkins G M
Proc Natl Acad Sci U S A. 1973 Apr;70(4):1088-9. doi: 10.1073/pnas.70.4.1088.
Treatment of polyoma virus-infected fibroblasts from mouse embryos and virus-infected 3T3 cells with physiological concentrations of the glucocorticoids enhances plaque formation at least 10-fold. The data suggest that this effect results from an increased rate of virus production. Steroid specificity studies indicate that the cytoplasmic receptors that mediate the physiological actions of these hormones are also involved in the present effect.
用生理浓度的糖皮质激素处理来自小鼠胚胎的多瘤病毒感染的成纤维细胞和病毒感染的3T3细胞,可使蚀斑形成增强至少10倍。数据表明,这种效应是由病毒产生速率增加所致。类固醇特异性研究表明,介导这些激素生理作用的细胞质受体也参与了目前这一效应。