Ito M, Barron A L
Infect Immun. 1973 Jul;8(1):48-521. doi: 10.1128/iai.8.1.48-52.1973.
Surface antigen(s) was demonstrated by the mixed agglutination technique on cell cultures infected with varicella-zoster virus (V-Z). The reactions appeared to be specific for V-Z, and no cross-reaction was obtained with herpes simplex virus (HSV). V-Z surface antigen had similar physicochemical properties to that of HSV. It was stable to heating at 56 C and treatment with 1% Formalin, 2,4-dinitrophenol, and periodate, whereas it was undetectable after exposure to acetone or ethanol. Antibodies detecting surface antigen were present in high titer in sera from varicella or herpes zoster patients and paralleled titers obtained by the complement fixation test.
采用混合凝集技术在感染水痘-带状疱疹病毒（V-Z）的细胞培养物上证实了表面抗原。这些反应似乎对V-Z具有特异性，与单纯疱疹病毒（HSV）未出现交叉反应。V-Z表面抗原具有与HSV相似的物理化学性质。它在56℃加热以及用1%福尔马林、2,4-二硝基苯酚和高碘酸盐处理后仍稳定，而在暴露于丙酮或乙醇后则无法检测到。检测表面抗原的抗体在水痘或带状疱疹患者的血清中呈高滴度存在，且与补体结合试验获得的滴度平行。
