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卤虫囊肿分化过程中的线粒体生物发生

Mitochondrial biogenesis during differentiation of Artemia salina cysts.

作者信息

Schmitt H, Grossfeld H, Littauer U Z

出版信息

J Cell Biol. 1973 Sep;58(3):643-9. doi: 10.1083/jcb.58.3.643.

Abstract

Mitochondria isolated from cysts of Artemia salina (brine shrimp) were found to be devoid of cristae and to possess a low respiratory capability. Hydration of the cysts induces marked biochemical and morphological changes in the mitochondria. Their biogenesis proceeds in two stages. The first stage is completed within 1 h and is characterized by a rapid increase in the respiratory capability of the mitochondria, their cytochrome oxidase, cytochrome b, cytochrome c and perhaps some morphological changes. In the second stage there is an increase in the protein-synthesizing capacity of the mitochondria as well as striking changes in mitochondrial morphology leading to the formation of cristae.

摘要

从卤虫(盐水虾)的囊肿中分离出的线粒体被发现没有嵴,且呼吸能力较低。囊肿的水化会诱导线粒体发生显著的生化和形态变化。它们的生物发生分两个阶段进行。第一阶段在1小时内完成,其特征是线粒体的呼吸能力、细胞色素氧化酶、细胞色素b、细胞色素c迅速增加,可能还会有一些形态变化。在第二阶段,线粒体的蛋白质合成能力增强,同时线粒体形态发生显著变化,导致嵴的形成。

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