Langness U, Udenfriend S
Proc Natl Acad Sci U S A. 1974 Jan;71(1):50-1. doi: 10.1073/pnas.71.1.50.
Prolyl hydroxylase and other enzymes of collagen synthesis have been found in cloned cells, including epithelium, melanoma, liver, HeLa, pituitary, kidney, and neuroblastoma. The significance of collagen biosynthesis in nonfibroblastic cells lines is discussed.
在克隆细胞中已发现脯氨酰羟化酶和其他胶原蛋白合成酶,这些克隆细胞包括上皮细胞、黑色素瘤细胞、肝细胞、海拉细胞、垂体细胞、肾细胞和成神经细胞瘤细胞。本文讨论了非成纤维细胞系中胶原蛋白生物合成的意义。