Lukás Z, Ludvikovský J
Cesk Patol. 1979 Feb;15(1):53-6.
Examination of 65 rectal biopsies and 10 resections by the histochemical detection of cholinesterase leads to the following conclusions: 1. Density of the nerve fibers in lamina propria is irregular and the examination of the cholinesterase activity may lead to falsely negative results in aganglionosis. 2. Constant is, in aganglionosis, the finding of markedly increased reaction in the nerve fibers of the muscularis mucosae and submucosa. 3. Biopsy must, therefore, include even muscularis mucosae and the choice of the instrument for biopsy removal must meet this requirement.
通过组织化学检测胆碱酯酶对65份直肠活检标本和10份切除术标本进行检查后得出以下结论：1. 固有层神经纤维密度不规则，胆碱酯酶活性检查在无神经节症中可能导致假阴性结果。2. 在无神经节症中，黏膜肌层和黏膜下层神经纤维反应明显增强这一发现是恒定的。3. 因此，活检必须包括黏膜肌层，并且用于活检取材的器械选择必须满足这一要求。
