Pour P, Krüger F W, Althoff J, Cardesa A, Mohr U
Am J Pathol. 1974 Aug;76(2):349-58.
A high incidence of pancreatic neoplasms was induced in Syrian golden hamsters following subcutaneous applications of diisopropanolnitrosamine (DIPN) once weekly for life. The tumor latency was as short as 15 weeks. In clinical and morphologic aspects the induced pancreatic tumors closely resembled those of humans.
通过每周一次皮下注射二异丙基亚硝胺(DIPN)直至动物生命结束,在叙利亚金黄地鼠中诱发了高发性胰腺肿瘤。肿瘤潜伏期短至15周。在临床和形态学方面,诱发的胰腺肿瘤与人类的胰腺肿瘤极为相似。