Reymann F
Dermatologica. 1979;158(5):368-72. doi: 10.1159/000250782.
During the period 1966-1968, 88 patients with a total of 95 basal cell carcinomas were treated with 5% 5-fluorouracil ointment. A follow-up study carried out from November 1977 to January 1978 revealed a total of 12 recurrences in 56 surviving patients with 56 basal cell carcinomas. The recurrence rate is thus 21.4%. It is concluded that there is hardly any indication for using 5-fluorouracil in local treatment of nodular basal cell carcinoma.
1966年至1968年期间,88例患者共95处基底细胞癌接受了5%氟尿嘧啶软膏治疗。1977年11月至1978年1月进行的一项随访研究发现,56例存活的基底细胞癌患者中共有12例复发。因此复发率为21.4%。结论是,在结节性基底细胞癌的局部治疗中几乎没有使用氟尿嘧啶的指征。