在存在产生翻译错误的试剂的情况下，大肠杆菌中分解代谢阻遏对β-半乳糖苷酶合成的抑制作用。
Catabolie repression in inhibition of beta-galactosidase synthesis by Escherichia coli in the presence of agents producing translation errors.
作者信息
Artman M, Werthamer S, Gelb P
出版信息
Antimicrob Agents Chemother. 1972 Dec;2(6):449-55. doi: 10.1128/AAC.2.6.449.
Abstract
Studies were made of the synthesis of beta-galactosidase by Escherichia coli in the presence of 5-fluorouracil, streptomycin, and subinhibitory concentrations of chloramphenicol. The preferential inhibition of beta-galactosidase synthesis observed in the presence of the above drugs was found to be caused by catabolite repression.
摘要
对大肠杆菌在5-氟尿嘧啶、链霉素和亚抑制浓度氯霉素存在的情况下合成β-半乳糖苷酶进行了研究。发现在上述药物存在的情况下观察到的对β-半乳糖苷酶合成的优先抑制是由分解代谢物阻遏引起的。
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本文引用的文献
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CHLORAMPHENICOL-PROMOTED REPRESSION OF beta-GALACTOSIDASE SYNTHESIS IN ESCHERICHIA COLI.氯霉素对大肠杆菌中β-半乳糖苷酶合成的促进性抑制作用
Proc Natl Acad Sci U S A. 1963 Mar;49(3):400-7. doi: 10.1073/pnas.49.3.400.
2
Mutants of Escherichia coli requiring methionine or vitamin B12.需要甲硫氨酸或维生素B12的大肠杆菌突变体。
J Bacteriol. 1950 Jul;60(1):17-28. doi: 10.1128/jb.60.1.17-28.1950.
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STREPTOMYCIN-INDUCED OVERSUPPRESSION IN E. COLI.链霉素诱导的大肠杆菌过度抑制
Proc Natl Acad Sci U S A. 1964 Jun;51(6):995-1001. doi: 10.1073/pnas.51.6.995.
4
PHENOTYPIC REPAIR BY STREPTOMYCIN OF DEFECTIVE GENOTYPES IN E. COLI.链霉素对大肠杆菌缺陷基因型的表型修复作用
Proc Natl Acad Sci U S A. 1964 Mar;51(3):487-93. doi: 10.1073/pnas.51.3.487.
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J Mol Biol. 1964 Jan;8:105-27. doi: 10.1016/s0022-2836(64)80153-4.
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