两种磷酸酯糖酵解中间体的膦酰甲基等排体的性质
Properties of the phosphonomethyl isosteres of two phosphate ester glycolytic intermediates.
作者信息
Stribling D
出版信息
Biochem J. 1974 Sep;141(3):725-8. doi: 10.1042/bj1410725.
Abstract
The enzymic synthesis of the 1-phosphonomethyl isostere of fructose 1,6-diphosphate in which the 1-phosphate (-OPO(3)H(2)) is replaced by the phosphonomethyl group (-CH(2)PO(3)H(2)) is described. The kinetic properties of this fructose diphosphate isostere and of 4-hydroxy-3-oxobutylphosphonic acid, an isostere of dihydroxyacetone phosphate, with aldolase (EC 4.1.2.13), fructose diphosphatase (EC 3.1.3.11) and glycerol phosphate dehydrogenase (EC 1.1.1.8) are described (see Table 1).
摘要
本文描述了果糖1,6 -二磷酸的1 -膦酰甲基类似物的酶促合成，其中1 -磷酸基团（-OPO(3)H(2)）被膦酰甲基基团（-CH(2)PO(3)H(2)）取代。还描述了这种果糖二磷酸类似物以及磷酸二羟丙酮的类似物4 -羟基-3 -氧代丁基膦酸与醛缩酶（EC 4.1.2.13）、果糖二磷酸酶（EC 3.1.3.11）和甘油磷酸脱氢酶（EC 1.1.1.8）的动力学性质（见表1）。
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本文引用的文献
1
OXIDATION OF REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE BY SOLUBLE RAT MUSCLE ALPHA-GLYCEROPHOSPHATE DEHYDROGENASE. A COMPARISON WITH PURIFIED LACTATE DEHYDROGENASE AND MALATE DEHYDROGENASE.可溶性大鼠肌肉α-甘油磷酸脱氢酶对还原型烟酰胺腺嘌呤二核苷酸磷酸的氧化作用。与纯化的乳酸脱氢酶和苹果酸脱氢酶的比较。
Biochim Biophys Acta. 1965 Feb 22;96:237-47.
2
Physical significance of Michaelis constants.米氏常数的物理意义。
Nature. 1962 Dec 22;196:1203-5. doi: 10.1038/1961203b0.
3
The determination of enzyme inhibitor constants.酶抑制剂常数的测定
Biochem J. 1953 Aug;55(1):170-1. doi: 10.1042/bj0550170.
4
Detection of phosphate esters on paper chromatograms.纸色谱图上磷酸酯的检测
Nature. 1953 Mar 21;171(4351):529-30. doi: 10.1038/171529a0.
5
Studies on the interaction of aldolase with substrate analogues.醛缩酶与底物类似物相互作用的研究。
J Biol Chem. 1969 Jan 10;244(1):126-34.
6
Aldolase: a model for enzyme structure-function relationships.醛缩酶：酶结构-功能关系的一个模型
Essays Biochem. 1972;8:149-78.
7
Dehydration of a phosphonate substrate analogue by glycerol 3-phosphate dehydrogenase.甘油3-磷酸脱氢酶催化膦酸酯底物类似物的脱水反应。
Biochem J. 1974 Sep;141(3):729-32. doi: 10.1042/bj1410729.
8
The interaction of the phosphonate analogue of 3-phospho-D-glycerate with phosphoglycerate kinase.3-磷酸-D-甘油酸的膦酸酯类似物与磷酸甘油酸激酶的相互作用。
Biochem J. 1974 Sep;141(3):721-3. doi: 10.1042/bj1410721.
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Biochim Biophys Acta. 1974 Mar 21;341(1):85-92. doi: 10.1016/0005-2744(74)90068-0.
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