向突触前神经元注射乙酰胆碱酯酶后，胆碱能突触的传递被阻断。 - Suppr

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超能文献

Transmission abolished on a cholinergic synapse after injection of acetylcholinesterase into the presynaptic neurone.

作者信息

Tauc L, Hoffmann A, Tsuji S, Hinzen D H, Faille L

出版信息

Nature. 1974 Aug 9;250(5466):496-8. doi: 10.1038/250496a0.

DOI:10.1038/250496a0

PMID:4377745

Abstract

摘要

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Transmission abolished on a cholinergic synapse after injection of acetylcholinesterase into the presynaptic neurone.向突触前神经元注射乙酰胆碱酯酶后，胆碱能突触的传递被阻断。

Nature. 1974 Aug 9;250(5466):496-8. doi: 10.1038/250496a0.

The physiological role of three acetylcholine receptors in synaptic transmission in Aplysia.三种乙酰胆碱受体在海兔突触传递中的生理作用。

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The effect of lidocaine on cholinergic neurotransmission in an identified reconstructed synapse.利多卡因对一个已鉴定的重建突触中胆碱能神经传递的影响。

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Presynaptic target of Ca2+ action on neuropeptide and acetylcholine release in Aplysia californica.加州海兔中Ca2+对神经肽和乙酰胆碱释放作用的突触前靶点。

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The action of chlorpromazine at an isolated cholinergic synapse.氯丙嗪在孤立胆碱能突触处的作用。

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L-glutamate blockade of transmission at the giant synapse of the squid stellate ganglion.L-谷氨酸对鱿鱼星状神经节巨大突触传递的阻断作用。

J Neurobiol. 1969;1(2):209-19. doi: 10.1002/neu.480010208.

Presynaptic actions of curare and atropine on quantal acetylcholine release at a central synapse of Aplysia.箭毒和阿托品对海兔中枢突触处量子化乙酰胆碱释放的突触前作用。

J Physiol. 1987 Jul;388:665-80. doi: 10.1113/jphysiol.1987.sp016637.

Morphine effects on cholinergic synaptic transmission in Aplysia: evidence for receptor blockade.

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引用本文的文献

Bromoacetylcholine and acetylcholinesterase introduced via liposomes into motor nerve endings block increases in quantal size.通过脂质体引入运动神经末梢的溴乙酰胆碱和乙酰胆碱酯酶可阻止量子大小的增加。

Pflugers Arch. 1996 Jul;432(3):413-8. doi: 10.1007/s004240050152.

Side effects of phosphorylated acetylcholinesterase reactivators on neuronal membrane and synaptic transmission.磷酸化乙酰胆碱酯酶复活剂对神经元膜及突触传递的副作用。

Pflugers Arch. 1983 Jan;396(1):8-14. doi: 10.1007/BF00584691.

Quantal release of acetylcholine examined by current fluctuation analysis at an identified neuro-neuronal synapse of Aplysia.通过电流波动分析在海兔一个已鉴定的神经-神经元突触处检测乙酰胆碱的量子释放。

Proc Natl Acad Sci U S A. 1980 Mar;77(3):1661-5. doi: 10.1073/pnas.77.3.1661.

Carbachol can be released at a cholinergic ganglionic synapse as a false transmitter.卡巴胆碱可作为一种假性递质在胆碱能神经节突触处释放。

Proc Natl Acad Sci U S A. 1983 Aug;80(16):5126-8. doi: 10.1073/pnas.80.16.5126.

Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.向细胞内注射环磷酸腺苷依赖性蛋白激酶的催化亚基，可模拟海兔行为敏化背后递质释放的易化过程。

Proc Natl Acad Sci U S A. 1980 Dec;77(12):7492-6. doi: 10.1073/pnas.77.12.7492.

Presynaptic actions of curare and atropine on quantal acetylcholine release at a central synapse of Aplysia.箭毒和阿托品对海兔中枢突触处量子化乙酰胆碱释放的突触前作用。

J Physiol. 1987 Jul;388:665-80. doi: 10.1113/jphysiol.1987.sp016637.

Presynaptic transmitter content controls the number of quanta released at a neuro-neuronal cholinergic synapse.突触前递质含量控制着神经-神经元胆碱能突触处释放的量子数量。

Proc Natl Acad Sci U S A. 1986 Jan;83(1):170-3. doi: 10.1073/pnas.83.1.170.

Both presynaptic nicotinic-like and muscarinic-like autoreceptors regulate acetylcholine release at an identified neuro-neuronal synapse of Aplysia.突触前烟碱样和毒蕈碱样自身受体均调节海兔特定神经-神经元突触处的乙酰胆碱释放。

Pflugers Arch. 1988 Apr;411(4):345-52. doi: 10.1007/BF00587712.

Neurotransmitter release is blocked intracellularly by botulinum neurotoxin, and this requires uptake of both toxin polypeptides by a process mediated by the larger chain.肉毒杆菌神经毒素在细胞内阻断神经递质释放，这需要通过由较大链介导的过程摄取两种毒素多肽。

Proc Natl Acad Sci U S A. 1988 Jun;85(11):4090-4. doi: 10.1073/pnas.85.11.4090.

In favour of the vesicular hypothesis: neurochemical evidence that vesamicol (AH5183) inhibits stimulation-evoked release of acetylcholine from neuromuscular junction.支持囊泡假说的证据：神经化学证据表明，vesamicol（AH5183）可抑制神经肌肉接头处由刺激诱发的乙酰胆碱释放。

Br J Pharmacol. 1989 Nov;98(3):898-902. doi: 10.1111/j.1476-5381.1989.tb14619.x.

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