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Conformational similarities between molecular models of phenethylamine and of potent inhibitors of the uptake of tritiated norepinephrine by adrenergic nerves in rabbit aorta.

作者信息

Maxwell R E, Chaplin E, Eckhardt S B, Soares J R, Hite G

出版信息

J Pharmacol Exp Ther. 1970 May;173(1):158-65.

PMID:4392603
Abstract
摘要

相似文献

1
Conformational similarities between molecular models of phenethylamine and of potent inhibitors of the uptake of tritiated norepinephrine by adrenergic nerves in rabbit aorta.苯乙胺分子模型与兔主动脉中肾上腺素能神经对氚化去甲肾上腺素摄取的强效抑制剂之间的构象相似性。
J Pharmacol Exp Ther. 1970 May;173(1):158-65.
2
Kinetic and thermodynamic considerations regarding the inhibition by tricyclic antidepressants of the uptake of tritiated norepinephrine by the adrenergic nerves in rabbit aortic strips.关于三环类抗抑郁药对兔主动脉条中肾上腺素能神经摄取氚化去甲肾上腺素的抑制作用的动力学和热力学考量。
J Pharmacol Exp Ther. 1970 Jan;171(1):62-9.
3
The phenyl rings of tricyclic antidepressants and related compounds as determinants of the potency of inhibition of the amine pumps in adrenergic neurons of the rabbit aorta and in rat cortical synaptosomes.
J Pharmacol Exp Ther. 1974 Dec;191(3):418-30.
4
Molecular features affecting the potency of tricyclic antidepressants and structurally related compounds as inhibitors of the uptake of tritiated norepinephrine by rabbit aortic strips.影响三环类抗抑郁药及结构相关化合物作为兔主动脉条摄取氚化去甲肾上腺素抑制剂效力的分子特征。
J Pharmacol Exp Ther. 1969 Apr;166(2):320-9.
5
A comparison of the capacities of isomers of amphetamine, deoxypipradrol and methylphenidate to inhibit the uptake of tritiated catecholamines into rat cerebral cortex slices, synaptosomal preparations of rat cerebral cortex, hypothalamus and striatum and into adrenergic nerves of rabbit aorta.对苯丙胺、脱氧哌甲酯和哌醋甲酯的异构体抑制氚标记儿茶酚胺摄取进入大鼠大脑皮层切片、大鼠大脑皮层、下丘脑和纹状体的突触体标本以及兔主动脉肾上腺素能神经的能力进行比较。
J Pharmacol Exp Ther. 1972 Jun;181(3):407-16.
6
The antagonism of phentolamine against exogenously administered and endogenously released norepinephrine in rabbit aortic strips.
J Pharmacol Exp Ther. 1970 Apr;172(2):310-9.
7
Concerning the distribution of endogenous norepinephrine in the adventitial and media-intimal layers of the rabbit aorta and the capacity of these layers to bind tritiated norepinephrine.关于内源性去甲肾上腺素在兔主动脉外膜和中膜-内膜层中的分布以及这些层结合氚标记去甲肾上腺素的能力。
J Pharmacol Exp Ther. 1968 May;161(1):34-9.
8
Structure-activity relationships for potent phthalane and thiophthalane inhibitors of norepinephrine uptake. A comparison with desipramine and related compounds.去甲肾上腺素摄取的强效苯酞和硫代苯酞抑制剂的构效关系。与地昔帕明及相关化合物的比较。
Mol Pharmacol. 1980 May;17(3):321-7.
9
Uptake, retention and metabolism of H 3 -tyramine in rat atria.大鼠心房中H³-酪胺的摄取、潴留和代谢
J Pharmacol Exp Ther. 1971 Jan;176(1):139-48.
10
[Animal experiments on the effect of ketamine on peripheral sympathetic nerves].
Anaesthesist. 1973 Mar;22(3):111-6.

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Transdermal and oral dl-methylphenidate-ethanol interactions in C57BL/6J mice: transesterification to ethylphenidate and elevation of d-methylphenidate concentrations.C57BL/6J 小鼠经皮和口服 dl-哌甲酯-乙醇相互作用：转酯化生成乙基哌甲酯和 d-哌甲酯浓度升高。
J Pharm Sci. 2011 Jul;100(7):2966-78. doi: 10.1002/jps.22476. Epub 2011 Jan 14.
2
Conformational analysis of methylphenidate and its structural relationship to other dopamine reuptake blockers such as CFT.哌醋甲酯的构象分析及其与其他多巴胺再摄取阻滞剂（如CFT）的结构关系。
Pharm Res. 1995 Oct;12(10):1430-4. doi: 10.1023/a:1016262815984.
3
Enantioselective pharmacokinetics of dl-threo-methylphenidate in humans.
Pharm Res. 1993 Jan;10(1):14-21. doi: 10.1023/a:1018956526016.
4
Stereospecific distribution of methylphenidate enantiomers in rat brain: specific binding to dopamine reuptake sites.哌醋甲酯对映体在大鼠脑中的立体特异性分布：与多巴胺再摄取位点的特异性结合。
Pharm Res. 1994 Mar;11(3):407-11. doi: 10.1023/a:1018917205292.
5
A quantitative study of the anticholinergic action of several tricyclic antidepressants on the rat isolated fundal strip.几种三环类抗抑郁药对大鼠离体胃底条抗胆碱能作用的定量研究。
Br J Pharmacol. 1972 Jul;45(3):519-24. doi: 10.1111/j.1476-5381.1972.tb08109.x.
6
Inhibition by tetrahydroharmane compounds of 5-hydroxytryptamine and histamine uptake in rabbit blood platelets.四氢哈尔满化合物对兔血小板中5-羟色胺和组胺摄取的抑制作用。
Naunyn Schmiedebergs Arch Pharmacol. 1973;279(4):361-70. doi: 10.1007/BF00500801.
7
Effects of antidepressant drugs on noradrenaline accumulation and contractile responses in the rat anococcygeus muscle.抗抑郁药物对大鼠肛尾肌去甲肾上腺素蓄积及收缩反应的影响。
Br J Pharmacol. 1977 Mar;59(3):403-9. doi: 10.1111/j.1476-5381.1977.tb08393.x.
8
Effects of drugs on the accumulation and spontaneous release of noradrenaline in the rat anococcygeus muscle.药物对大鼠肛尾肌去甲肾上腺素蓄积及自发释放的影响。
Br J Pharmacol. 1978 Jul;63(3):465-70. doi: 10.1111/j.1476-5381.1978.tb07798.x.