Poller L, Priest C M, Thomson J M
Br Med J. 1969 Nov 1;4(5678):273-4. doi: 10.1136/bmj.4.5678.273.
Platelet aggregation has been found to be significantly accelerated with the coagulation-induced Chandler's tube technique in women taking combined oestrogen-progestin oral contraceptives, though this was less than in the third trimester of pregnancy. Women taking the pure progestogen, chlormadinone acetate, have not shown this change up to the sixth month of study. In contrast the accelerated platelet aggregation resulting from conventional oral contraception became normal one month after changing to the progestogen. There was no change in the platelet aggregation response to adenosine diphosphate (A.D.P.) during oral contraception.
采用凝血诱导的钱德勒管技术发现，服用复方雌激素 - 孕激素口服避孕药的女性血小板聚集显著加速，不过这一加速程度低于妊娠晚期。服用单纯孕激素醋酸氯地孕酮的女性在研究的六个月内未出现这种变化。相比之下，由传统口服避孕药引起的血小板聚集加速在改用孕激素后一个月恢复正常。口服避孕药期间，血小板对二磷酸腺苷（A.D.P.）的聚集反应没有变化。
