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Pharmacokinetics of lithium and its regional distribution in rat brain.

作者信息

Ebadi M S, Simmons V J, Hendrickson M J, Lacy P S

出版信息

Eur J Pharmacol. 1974 Aug;27(3):324-9. doi: 10.1016/0014-2999(74)90007-7.

DOI:10.1016/0014-2999(74)90007-7
PMID:4422028
Abstract
摘要

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1
Pharmacokinetics of lithium and its regional distribution in rat brain.锂在大鼠体内的药代动力学及其在大鼠脑内的区域分布
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Accumulation of lithium in the particulate fraction of rat brain following its long-term administration.
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Determination of lithium in rat brain regions and synaptosomes by graphite furnace atomic absorption spectrophotometry.用石墨炉原子吸收分光光度法测定大鼠脑区和突触体中的锂
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Plasma and brain lithium levels after lithium carbonate and lithium chloride administration by different routes in rats.大鼠经不同途径给予碳酸锂和氯化锂后血浆及脑内锂水平
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Rat brain and serum lithium concentrations after acute injections of lithium carbonate and orotate.
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[Distribution of lithium in the brain and blood serum of mice after single and chronic administration].[单次及长期给药后锂在小鼠脑和血清中的分布]
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The prediction of brain lithium concentrations from plasma or erythrocyte measures.通过血浆或红细胞测量值预测脑锂浓度。
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Lithium administered to pregnant, lactating and neonatal rats: entry into developing brain.锂在怀孕、哺乳期和新生大鼠中的给药:进入发育中的大脑。
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双相障碍患者脑内锂离子分布的 3D Li 磁共振成像
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Improving lithium therapeutics by crystal engineering of novel ionic cocrystals.通过新型离子共晶的晶体工程改善锂治疗。
Mol Pharm. 2013 Dec 2;10(12):4728-38. doi: 10.1021/mp400571a. Epub 2013 Nov 18.
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Lithium: updated human knowledge using an evidence-based approach. Part II: Clinical pharmacology and therapeutic monitoring.锂:采用循证方法更新人类知识。第二部分:临床药理学与治疗监测。
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Hyperpolarized lithium-6 as a sensor of nanomolar contrast agents.超极化锂-6作为纳摩尔造影剂的传感器。
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Toxicity and renal elimination of lithium in rats of different ages.
Arch Toxicol. 1981 Apr;47(2):135-44. doi: 10.1007/BF00332355.
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