正常受试者和气道阻塞患者使用支气管扩张剂后一秒钟内特定气道传导率和用力呼气量的变化。
Changes in specific airways conductance and forced expiratory volume in one second after a bronchodilator in normal subjects and patients with airways obstruction.
作者信息
Skinner C, Palmer K N
出版信息
Thorax. 1974 Sep;29(5):574-7. doi: 10.1136/thx.29.5.574.
Abstract
, 574-577. Specific conductance (SGaw) and the forced expiratory volume in one second (FEV) were measured in 10 normal, 10 asthmatic, and 10 obstructive bronchitic subjects before and after aerosol salbutamol. Mean SGaw increased by 37% in normals, by 109% in asthmatics, and by 38% in obstructive bronchitics. Mean FEV increased by 2% in normals, by 32% in asthmatics, and by 12% in obstructive bronchitics. SGaw appears to be a more sensitive indicator than FEV of changes in airways calibre following a bronchodilator drug in normal subjects, but FEV is as good an indicator of these changes as SGaw in patients with airways obstruction.
摘要
在10名正常受试者、10名哮喘患者和10名阻塞性支气管炎患者吸入沙丁胺醇气雾剂前后，测量了比电导（SGaw）和一秒用力呼气量（FEV）。正常受试者的平均SGaw增加了37%，哮喘患者增加了109%，阻塞性支气管炎患者增加了38%。正常受试者的平均FEV增加了2%，哮喘患者增加了32%，阻塞性支气管炎患者增加了12%。在正常受试者中，SGaw似乎比FEV更能敏感地反映支气管扩张剂药物后气道管径的变化，但在气道阻塞患者中，FEV与SGaw一样是这些变化的良好指标。
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