Galbo H, Hilsted J, Fahrenkrug J, Schaffalitzky De Muckadell O B
Acta Physiol Scand. 1979 Mar;105(3):374-7. doi: 10.1111/j.1748-1716.1979.tb06353.x.
6 young men had venous blood drawn during 4 experiments. The concentration of VIP in plasma increased markedly (from 1.8 (0--4.5) to 22.3 (7.8--43.8) pmol.1(-1), mean and range) during 3 h of mild bicycle exercise but not at all during an equivalent period of rest or during short term submaximal and maximal exercise. During 59 h of fasting, VIP increased from 3.6 (0.6--6.6) to 10.2 (6.6--13.8) pmol.1(-1) (p less than 0.05). The concentration of glucose in plasma decreased significantly during the prolonged exercise as well as during fasting. The known metabolic actions of VIP and the demonstrated increases in its plasma concentration during negative energy balance indicate that VIP is "a polypeptide of substrate need".
6名年轻男性在4项实验中接受了静脉采血。在轻度自行车运动3小时期间，血浆中血管活性肠肽（VIP）的浓度显著增加（从1.8（0 - 4.5）升至22.3（7.8 - 43.8）pmol·L⁻¹，均值及范围），但在同等时长的休息期间或短期次最大强度和最大强度运动期间则完全没有变化。在禁食59小时期间，VIP从3.6（0.6 - 6.6）升至10.2（6.6 - 13.8）pmol·L⁻¹（p < 0.05）。在长时间运动以及禁食期间，血浆中的葡萄糖浓度显著降低。VIP已知的代谢作用以及在负能量平衡期间其血浆浓度的显著升高表明，VIP是“一种底物需求的多肽”。
