Weiss G, Hechtman L, Perlman T, Hopkins J, Wener A
Arch Gen Psychiatry. 1979 Jun;36(6):675-81. doi: 10.1001/archpsyc.1979.01780060065007.
This study reports on a variety of outcome variables from 75 hyperactive and 44 matched control subjects aged 17 to 24 years (mean ages, 19.5 and 19.0 years, respectively). All hyperactive subjects have been followed up for 10 to 12 years; they were first evaluated at 6 to 12 years of age. None of the hyperactive subjects was treated with methylphenidate, although a subgroup received chlorpromazine or a mixture of drugs (excluding methylphenidate). The hyperactive subjects had less education than the controls and a history of more car accidents and more geographical moves. However, only a minority were still engaged in continued antisocial behavior or had evidence of severe psychopathology. No subjects were found to be psychotic, but two were diagnosed as borderline psychotic. There was evidence that hyperactive subjects had some continued symptoms from the hyperkinetic child syndrome, including impulsive personality traits.
本研究报告了75名17至24岁（平均年龄分别为19.5岁和19.0岁）的多动受试者和44名匹配的对照受试者的各种结果变量。所有多动受试者均已随访10至12年；他们首次评估时年龄为6至12岁。尽管有一个亚组接受了氯丙嗪或药物混合物（不包括哌醋甲酯）治疗，但没有一名多动受试者接受过哌醋甲酯治疗。多动受试者的受教育程度低于对照组，且有更多交通事故和更多搬家经历。然而，只有少数人仍在持续从事反社会行为或有严重精神病理学证据。未发现受试者患有精神病，但有两人被诊断为边缘性精神病。有证据表明，多动受试者仍有一些来自多动儿童综合征的持续症状，包括冲动型人格特质。
