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1
Antibody-dependent and spontaneous lympholysis in urologic cancer patients.泌尿系统癌症患者的抗体依赖性和自发性淋巴细胞溶解
Br J Cancer. 1979 Jun;39(6):667-75. doi: 10.1038/bjc.1979.118.
2
Cytotoxicity of human peripheral lymphocytes in cell-mediated lympholysis; antibody-dependent cell-mediated lympholysis and natural cytotoxicity assays after mixed lymphocyte culture.细胞介导性淋巴细胞溶解中人类外周淋巴细胞的细胞毒性；混合淋巴细胞培养后的抗体依赖性细胞介导的细胞毒性及自然细胞毒性检测
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Discordance among cell-mediated cytolytic mechanisms in cancer patients: importance of the assay system.癌症患者细胞介导的细胞溶解机制之间的不一致：检测系统的重要性。
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[The significance of lymphocytic infiltration in urologic tumors: studies of distributions of B and T-lymphocytes and its subsets, and functional analysis of the infiltrating lymphocytes (author's transl)].[淋巴细胞浸润在泌尿系统肿瘤中的意义：B和T淋巴细胞及其亚群分布的研究以及浸润淋巴细胞的功能分析（作者译）]
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[Effect of a delayed type hypersensitivity reaction on the cytotoxic activity of macrophages, natural and antibody-dependent killer cells].[迟发型超敏反应对巨噬细胞、自然杀伤细胞及抗体依赖性杀伤细胞细胞毒活性的影响]
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Clonal expansion of human B73.1-positive natural killer cells or large granular lymphocytes exerting strong antibody-dependent and -independent cytotoxicity and occasionally lectin-dependent cytotoxicity.人类B73.1阳性自然杀伤细胞或大颗粒淋巴细胞的克隆性扩增，这些细胞具有强大的抗体依赖性和非依赖性细胞毒性，偶尔还具有凝集素依赖性细胞毒性。
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9
An Fc engineering approach that modulates antibody-dependent cytokine release without altering cell-killing functions.一种Fc工程方法，可调节抗体依赖性细胞因子释放而不改变细胞杀伤功能。
MAbs. 2015;7(3):494-504. doi: 10.1080/19420862.2015.1022692.
10
Characterisation of the effector cells in antibody-dependent and spontaneous cell-mediated cytotoxicity in swine against target cells infected with transmissible gastroenteritis virus.猪体内抗体依赖性和自发性细胞介导的细胞毒性中效应细胞对感染传染性胃肠炎病毒的靶细胞作用的特征分析
Res Vet Sci. 1986 Jul;41(1):70-5.

引用本文的文献

1
Natural killer cells are crucial for the efficacy of Icon (factor VII/human IgG1 Fc) immunotherapy in human tongue cancer.自然杀伤细胞对于 Icon（因子 VII/人 IgG1 Fc）免疫疗法在人类舌癌中的疗效至关重要。
BMC Immunol. 2010 Oct 12;11:49. doi: 10.1186/1471-2172-11-49.

本文引用的文献

1
Phagocytosis of immune complexes by macrophages. Different roles of the macrophage receptor sites for complement (C3) and for immunoglobulin (IgG).巨噬细胞对免疫复合物的吞噬作用。巨噬细胞补体（C3）受体位点和免疫球蛋白（IgG）受体位点的不同作用。
J Exp Med. 1972 Apr 1;135(4):780-92. doi: 10.1084/jem.135.4.780.
2
Antibody induction of lymphocyte-mediated cytotoxicity against human transitional-cell carcinomas of the urinary tract.抗体诱导淋巴细胞介导的针对人泌尿道移行细胞癌的细胞毒性作用。
N Engl J Med. 1974 Sep 26;291(13):637-41. doi: 10.1056/NEJM197409262911301.
3
Reactivity of lymphocytes from normal persons on cultured tumor cells.正常人淋巴细胞对培养肿瘤细胞的反应性。
Cancer Res. 1973 Nov;33(11):2898-902.
4
Depressed lymphocyte-mediated killing of sensitized targets in cancer patients.癌症患者中淋巴细胞介导的对致敏靶标的杀伤作用降低。
Cancer Res. 1974 Oct;34(10):2694-8.
5
Cell-mediate cytotoxicity in vitro of human lymphocytes against a tissue culture melanoma cell line (igr3).人淋巴细胞对一种组织培养黑色素瘤细胞系（igr3）的体外细胞介导细胞毒性。
J Immunol. 1975 Aug;115(2):539-48.
6
Antibody dependent cytolytic effector lymphocytes (K cells) in human blood.人血液中的抗体依赖性细胞溶解效应淋巴细胞（K细胞）。
J Reticuloendothel Soc. 1975 Apr;17(4):241-50.
7
The effector cells in human peripheral blood mediating mitogen-induced cellular cytotoxicity and antibody-dependent cellular cytotoxicity.介导有丝分裂原诱导的细胞毒性和抗体依赖性细胞毒性的人外周血中的效应细胞。
J Immunol. 1976 Nov;117(5 Pt 1):1472-81.
8
Killer cells: a functional comparison between natural, immune T-cell and antibody-dependent in vitro systems.杀伤细胞：天然杀伤细胞、免疫T细胞与抗体依赖体外系统之间的功能比较
J Exp Med. 1976 Apr 1;143(4):772-80. doi: 10.1084/jem.143.4.772.
9
Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells.小鼠淋巴细胞对同基因和异基因肿瘤的天然细胞毒性反应。II. 效应细胞的特性
Int J Cancer. 1975 Aug 15;16(2):230-9. doi: 10.1002/ijc.2910160205.
10
Antibody-dependent cell-mediated cytotoxicity in treated and nontreated cancer patients.接受治疗和未接受治疗的癌症患者体内的抗体依赖性细胞介导的细胞毒性作用
Cancer. 1977 Sep;40(3):1045-51. doi: 10.1002/1097-0142(197709)40:3<1045::aid-cncr2820400312>3.0.co;2-b.

泌尿系统癌症患者的抗体依赖性和自发性淋巴细胞溶解

Antibody-dependent and spontaneous lympholysis in urologic cancer patients.

作者信息

Ratliff T L, McCool R E, Catalona W J

出版信息

Br J Cancer. 1979 Jun;39(6):667-75. doi: 10.1038/bjc.1979.118.

DOI:10.1038/bjc.1979.118
PMID:444405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2009983/
Abstract

To evaluate cytotoxic function mediated by killer lymphocytes and macrophages in urological cancer patients, we examined antibody-dependent and spontaneous lympholysis of chicken erythrocyte target cells, which is mediated by macrophages. Our results demonstrate a discordance between cytotoxic mechanisms in cancer patients, killer-cell function being impaired whilst macrophage-mediated cytotoxicity was increased.

摘要

为评估泌尿系统癌症患者中杀伤性淋巴细胞和巨噬细胞介导的细胞毒性功能，我们检测了巨噬细胞介导的鸡红细胞靶细胞的抗体依赖性和自发性淋巴细胞溶解。我们的结果表明癌症患者的细胞毒性机制存在差异，杀伤细胞功能受损，而巨噬细胞介导的细胞毒性增加。