Stratton M L, Herz J, Loeffler R A, McClurg F L, Reiter A, Bernstein P, Danley D L, Benjamini E
Cancer. 1977 Sep;40(3):1045-51. doi: 10.1002/1097-0142(197709)40:3<1045::aid-cncr2820400312>3.0.co;2-b.
Antibody-dependent cell-mediated cytotoxicity (ADCC) exhibited by peripheral blood leukocytes was used as a criterion for assessing immune competence of groups of noncancerous individuals and of treated and untreated cancer patients. The results show that, as a group, leukocytes of nontreated cancer patients exhibited significantly lower ADCC than that exhibited by leukocytes of noncancerous individuals. However, the ADCC of leukocytes from cancer patients under treatment approximated that of normals. Thus, using ADCC as criterion, the results indicate that as a group, cancer patients under treatment tend to exhibit restored immune competence.
外周血白细胞表现出的抗体依赖性细胞介导的细胞毒性（ADCC）被用作评估非癌症个体组以及治疗和未治疗癌症患者免疫能力的标准。结果表明，作为一个群体，未治疗癌症患者的白细胞表现出的ADCC显著低于非癌症个体白细胞表现出的ADCC。然而，接受治疗的癌症患者白细胞的ADCC接近正常水平。因此，以ADCC为标准，结果表明，作为一个群体，接受治疗的癌症患者往往表现出恢复的免疫能力。
