癌症巨噬细胞电泳迁移率试验的临床评估
Clinical evaluation of the macrophage electrophoretic mobility test for cancer.
作者信息
Lewkonia R M, Kerr E J, Irvine W J
出版信息
Br J Cancer. 1974 Dec;30(6):532-7. doi: 10.1038/bjc.1974.232.
Abstract
Experience with the macrophage electrophoretic mobility (MEM) test of Field and Caspary in subjects with malignant and non-malignant disease is reported. There was some discrimination between groups of patients with benign and malignant lesions but there was no clear separation between the groups. A trial of the Cardiff modification of the test failed to discriminate between groups of patients with benign and malignant chest disease. In the view of the authors the MEM test in its present form is not sufficiently reproducible to warrant more general clinical application as an in vitro test for cancer.
摘要
报告了菲尔德和卡斯帕里对患有恶性和非恶性疾病的受试者进行巨噬细胞电泳迁移率（MEM）测试的经验。良性和恶性病变患者组之间存在一定的区分，但两组之间没有明显的分离。对该测试的加的夫改良版进行的试验未能区分患有良性和恶性胸部疾病的患者组。作者认为，目前形式的MEM测试的可重复性不足，不足以保证作为癌症的体外测试更广泛地应用于临床。
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本文引用的文献
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Lymphocyte-antigen interaction in electrophoretic mobility test for cellular sensitization.细胞致敏电泳迁移率试验中的淋巴细胞-抗原相互作用。
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Br J Cancer. 1973 Jan;27(1):1-9. doi: 10.1038/bjc.1973.1.
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Specific lymphocyte sensitization in cancer: is there a common antigen in human malignant neoplasia?癌症中的特异性淋巴细胞致敏：人类恶性肿瘤中是否存在共同抗原？
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