评估巨噬细胞电泳迁移率（MEM）试验作为眼部肿瘤细胞免疫指标的作用。
Evaluation of macrophage electrophoretic mobility (MEM) test as an indicator of cellular immunity in ocular tumours.
作者信息
Rahi A H, Otiko G, Winder A F
出版信息
Br J Ophthalmol. 1976 Aug;60(8):589-93. doi: 10.1136/bjo.60.8.589.
Abstract
The macrophage electrophoretic mobility (MEM) test of Field and Caspary did not clearly separate patients with ocular neoplastic disease from those with inflammatory disease, although there was some indication of discrimination between choroidal melanoma and ocular inflammation. In our hands the test failed to give a reproducible result for the immunodiagnosis of ocular malignancy. The technique, however, seems to provide some indication of delayed hypersensitivity in experimental inflammatory eye diseases when relatively pure antigens are used.
摘要
菲尔德和卡斯帕里的巨噬细胞电泳迁移率（MEM）试验，未能明确区分眼部肿瘤疾病患者和炎症性疾病患者，尽管在脉络膜黑色素瘤与眼部炎症之间有一些鉴别迹象。在我们的操作中，该试验未能为眼部恶性肿瘤的免疫诊断提供可重复的结果。然而，当使用相对纯的抗原时，这项技术似乎能为实验性炎性眼病中的迟发型超敏反应提供一些迹象。
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本文引用的文献
1
DELAYED HYPERSENSITIVITY IN VITRO. I. THE SPECIFICITY OF INHIBITION OF CELL MIGRATION BY ANTIGENS.
J Immunol. 1964 Aug;93:264-73.
2
Electrophoretic mobilities of antigen-stimulated lymph node cells.
Immunology. 1967 Jan;12(1):21-6.
3
The detection by cellular electrophoresis of surface antibodies on human lymphocytes.
Clin Exp Immunol. 1969 Dec;5(6):669-72.
4
Autoimmune reactions in uveal melanoma.
Br J Ophthalmol. 1971 Dec;55(12):793-807. doi: 10.1136/bjo.55.12.793.
5
6
Clinical evaluation of the macrophage electrophoretic mobility test for cancer.
Br J Cancer. 1974 Dec;30(6):532-7. doi: 10.1038/bjc.1974.232.
7
The isolation and properties of experimental allergic encephalitogenic protein.
Biochem J. 1969 Mar;111(5):629-36. doi: 10.1042/bj1110629.
8
Immunofluorescent detection of antibodies to ocular melanomas.
Arch Ophthalmol. 1974 Aug;92(2):98-102. doi: 10.1001/archopht.1974.01010010104004.
9
Macrophage-electrophoretic-mobility (M.E.M.) test for malignant disease. An independent confirmation.
Lancet. 1972 Sep 23;2(7778):627-9. doi: 10.1016/s0140-6736(72)93018-8.
10
Lymphocyte sensitisation: an in-vitro test for cancer?
Lancet. 1970 Dec 26;2(7687):1337-41. doi: 10.1016/s0140-6736(70)92361-5.
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