普萘洛尔对白化病大鼠胃液分泌的影响。
Effects of propranolol on gastric secretion in albino rats.
作者信息
Debnath P K, Gode K D, Das D G, Sanyal A K
出版信息
Br J Pharmacol. 1974 Jun;51(2):213-6. doi: 10.1111/j.1476-5381.1974.tb09649.x.
Abstract
1 Effects of graded doses of propranolol have been studied on gastric secretion and gastric ulcers in pylorus-ligated rats.2 A dose-dependent action of propranolol was observed; small doses increased total volume, acid output and pepsin secretion along with an increase in the incidence of ulcers but high doses were inhibitory.
摘要
已对不同剂量普萘洛尔对幽门结扎大鼠胃分泌及胃溃疡的影响进行了研究。
观察到普萘洛尔具有剂量依赖性作用；小剂量会增加总体积、酸分泌量和胃蛋白酶分泌，同时溃疡发生率增加，但大剂量则具有抑制作用。
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