Friis N F
Acta Vet Scand. 1974;15(4):507-18. doi: 10.1186/BF03547222.
Three field strains of Mycoplasma suipneumoniae each inoculated into 3 gnotobiotic piglets produced macro- and microscopic lung lesions typical of enzootic pneumonia in 8 of the animals. Under similar conditions 3 strains of M. flocculare produced typical macroscopic lung lesions in just 1 out of 9 animals. It is therefore concluded that M. flocculare is not of primary etiologic importance in the porcine enzootic pneumonia complex. The frequency of successful reisolation from nasal cavities, lungs, and other tissues indicated that the lungs are the sole natural habitat for M. suipneumoniae, while for M. flocculare lungs as well as nasal cavities should be regarded as the natural habitat. None of the organisms apparently spread via the blood stream. M. flocculare, but not M. suipneumoniae, induced histologic alterations of the nasal mucosa.
将三株猪肺炎支原体野毒株分别接种到3头无菌仔猪体内,8只动物出现了典型的地方性肺炎的大体和微观肺部病变。在类似条件下,三株絮状支原体仅在9只动物中的1只身上产生了典型的大体肺部病变。因此得出结论,絮状支原体在猪地方性肺炎综合征中并非主要病因。从鼻腔、肺部和其他组织成功再分离的频率表明,肺部是猪肺炎支原体的唯一自然栖息地,而对于絮状支原体来说,肺部和鼻腔都应被视为自然栖息地。显然,这些微生物都不会通过血流传播。絮状支原体而非猪肺炎支原体可引起鼻黏膜的组织学改变。