Overgaard K, Overgaard J
Acta Radiol Ther Phys Biol. 1974 Dec;13(6):501-11. doi: 10.3109/02841867409132649.
The radiation sensitizing effect of heat is analysed. In an isologous mouse-tumour system a successive local exposition to heat and roentgen irradiation with doses of both components of a size expected separately to give no or a few cures only an evident rise in the curative results was obtained. The presence of a synergism of the factors applied is suggested. The effect obtained depends on the dose of both factors. It is independent of the sequence of the application of the two components and is not reduced by an interval of 24 h between the exposures.
分析了热的辐射增敏作用。在同基因小鼠肿瘤系统中，对肿瘤进行连续局部加热和X射线照射，两种成分的剂量单独使用时预期只能产生极少治愈或无法治愈的效果，但联合使用后却显著提高了治愈效果。提示所应用的因素之间存在协同作用。所获得的效果取决于两种因素的剂量。它与两种成分的应用顺序无关，且两次照射之间间隔24小时也不会降低效果。
