神经氨酸酶增强癌症患者迟发性皮肤超敏反应。
Enhancement of delayed skin hypersensitivity by neuraminidase in cancer patients.
作者信息
Han T
出版信息
Clin Exp Immunol. 1974 Sep;18(1):95-100.
Abstract
Delayed skin hypersensitivity to specific antigen was enhanced when the antigen was given intradermally with neuraminidase in sensitive subjects. No enhancement of skin test response was seen when inactivated enzyme was used. Neuraminidase exhibited no effect on negative skin-test response in non-sensitive recipients and no reaction at the site of this enzyme was observed in any instance, suggesting that the enhancement effect is immunological in nature.
摘要
在敏感个体中，当抗原与神经氨酸酶一起皮内注射时，对特定抗原的迟发性皮肤超敏反应会增强。使用灭活酶时，未观察到皮肤试验反应增强。神经氨酸酶对非敏感接受者的阴性皮肤试验反应无影响，且在任何情况下均未在该酶注射部位观察到反应，这表明增强作用本质上是免疫性的。
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