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携带二氢嘧啶核苷磷酸酶诱导性胰腺癌的金黄仓鼠中的核糖核酸酶水平

RNase levels in golden hamster with DHPN induced pancreatic cancer.

作者信息

Walton D, Nakazawa S, Kajikawa M, Naito Y, Ichikawa M, Kimoto E, Sano H, Suzuki Y, Asai T

出版信息

Gastroenterol Jpn. 1979;14(1):74-9. doi: 10.1007/BF02774607.

DOI:10.1007/BF02774607
PMID:446989
Abstract

Twenty Syrian golden hamsters recieved weekly injections of pancreatic cancer inducing DHPN. Their Poly (U) specific serum RNase levels were significantly elevated when compared to the control levels. Following salt fractionation, Poly (U) specific activity was present in both the 40% and 50% salt saturated fractions. Tissue assays showed that Poly (U) specific RNase was present in both pancreas and liver tissue extract, although the liver tissue RNase had a different pH maximum than that of the serum RNase.

摘要

二十只叙利亚金黄地鼠每周接受诱导胰腺癌的DHPN注射。与对照水平相比,它们的聚(U)特异性血清核糖核酸酶水平显著升高。盐分级分离后,聚(U)特异性活性存在于40%和50%盐饱和级分中。组织分析表明,胰腺和肝组织提取物中均存在聚(U)特异性核糖核酸酶,尽管肝组织核糖核酸酶的最适pH值与血清核糖核酸酶不同。

相似文献

1
RNase levels in golden hamster with DHPN induced pancreatic cancer.携带二氢嘧啶核苷磷酸酶诱导性胰腺癌的金黄仓鼠中的核糖核酸酶水平
Gastroenterol Jpn. 1979;14(1):74-9. doi: 10.1007/BF02774607.
2
Changes of amylase during experimental pancreatic carcinogenesis in hamsters.仓鼠实验性胰腺癌发生过程中淀粉酶的变化
Gan. 1981 Aug;72(4):615-9.
3
[Changes of RNase activity on DIPN induced experimental pancreatic cancer (author's transl)].二异丙基萘诱导的实验性胰腺癌中核糖核酸酶活性的变化(作者译)
Nihon Shokakibyo Gakkai Zasshi. 1980 Nov;77(11):1766-9.
4
[Studies of DHPN induced pancreatic carcinoma with emphasis on pancreatography (author's transl)].以胰造影术为重点的二氢吡啶诱导胰腺癌的研究(作者译)
Nihon Shokakibyo Gakkai Zasshi. 1978 Sep;75(9):1386-98.
5
Enzyme histochemical studies on transplantable pancreatic adenocarcinomas in Syrian golden hamsters.叙利亚金黄地鼠可移植性胰腺腺癌的酶组织化学研究。
Exp Pathol. 1984;26(4):205-11. doi: 10.1016/s0232-1513(84)80051-1.
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Experimental pancreatic carcinogenesis. II. Lifetime carcinogenesis studies in the outbred Syrian golden hamster with N-nitroso-bis(2-hydroxypropyl)amine.实验性胰腺癌发生。II. 用N-亚硝基双(2-羟丙基)胺对远交叙利亚金黄地鼠进行终生致癌研究。
J Natl Cancer Inst. 1978 Mar;60(3):701-5. doi: 10.1093/jnci/60.3.701.
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[Histological characteristics of pancreatic carcinoma induced by N-nitrosobis (2-hydroxypropyl) amine in Syrian golden hamster].[叙利亚金黄地鼠中N-亚硝基双(2-羟丙基)胺诱导的胰腺癌的组织学特征]
Nihon Shokakibyo Gakkai Zasshi. 1982 Sep;79(9):1771-7.
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A further pancreatic carcinogen in Syrian golden hamsters: N-nitroso-bis(2-acetoxypropyl)amine.叙利亚金黄地鼠体内的另一种胰腺致癌物:N-亚硝基双(2-乙酰氧基丙基)胺。
Cancer Lett. 1976 Mar;1(4):197-202. doi: 10.1016/s0304-3835(75)96702-6.
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A new approach for induction of pancreatic neoplasms.一种诱导胰腺肿瘤的新方法。
Cancer Res. 1975 Aug;35(8):2259-68.
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Experimental pancreatic carcinogenesis. I. Morphogenesis of pancreatic adenocarcinoma in the Syrian golden hamster induced by N-nitroso-bis(2-hydroxypropyl)amine.实验性胰腺癌发生。I. N-亚硝基双(2-羟丙基)胺诱导叙利亚金仓鼠胰腺腺癌的形态发生
Am J Pathol. 1977 Jul;88(1):5-28.

本文引用的文献

1
Cancer of the pancreas induced in the Syrian golden hamster.叙利亚金黄地鼠诱发的胰腺癌。
Am J Pathol. 1974 Aug;76(2):349-58.
2
A new approach for induction of pancreatic neoplasms.一种诱导胰腺肿瘤的新方法。
Cancer Res. 1975 Aug;35(8):2259-68.
3
Cancers of the pancreas and biliary tract: epidemiological considerations.胰腺癌和胆管癌:流行病学考量
Cancer Res. 1975 Nov;35(11 Pt. 2):3437-46.
4
Elevated serum ribonuclease in patients with pancreatic cancer.胰腺癌患者血清核糖核酸酶升高。
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2308-10. doi: 10.1073/pnas.73.7.2308.
5
Pancreatic secretion in hamsters with pancreatic cancer.患有胰腺癌的仓鼠的胰腺分泌情况。
Surgery. 1977 Jul;82(1):34-41.
6
[Studies of DHPN induced pancreatic carcinoma with emphasis on pancreatography (author's transl)].以胰造影术为重点的二氢吡啶诱导胰腺癌的研究(作者译)
Nihon Shokakibyo Gakkai Zasshi. 1978 Sep;75(9):1386-98.
7
Nature and possible origin of human serum ribonuclease.人血清核糖核酸酶的性质及可能起源
Biochem Biophys Res Commun. 1975 Nov 3;67(1):110-8. doi: 10.1016/0006-291x(75)90290-9.