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石棉纤维对细胞的穿透作用。

Penetration of cells by asbestos fibers.

作者信息

Davis J M, Bolton R E, Garrett J

出版信息

Environ Health Perspect. 1974 Dec;9:255-60. doi: 10.1289/ehp.749255.

Abstract

Studies on the behavior of asbestos fibers within tissues have shown that the only cells that regularly contain asbestos are macrophages and their derivatives. However, these cells actively incorporate the asbestos fibers by the process of phagocytosis, and there is little evidence of direct penetration. Examination of the gut lining after prolonged asbestos ingestion has shown no evidence of dust penetration either through or between the epithelial cells. The structure and arrangement of these cells is discussed, and it is suggested that they are exceptionally well adapted to prevent penetration by any solid material.

摘要

对石棉纤维在组织内行为的研究表明,正常含有石棉的唯一细胞是巨噬细胞及其衍生物。然而,这些细胞通过吞噬过程积极摄取石棉纤维,几乎没有直接穿透的证据。长期摄入石棉后对肠壁的检查表明,没有证据显示灰尘通过上皮细胞或在上皮细胞之间穿透。文中讨论了这些细胞的结构和排列,并指出它们具有非凡的适应性以防止任何固体物质穿透。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84cf/1475371/448eadc3c7e2/envhper00499-0248-a.jpg

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