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Clinical application for heavy metal-complexing potential of N-acetylcysteine.

作者信息

Lorber A, Baumgartner W A, Bovy R A, Chang C C, Hollcraft R

出版信息

J Clin Pharmacol. 1973 Aug-Sep;13(8):332-6. doi: 10.1002/j.1552-4604.1973.tb00220.x.

DOI:10.1002/j.1552-4604.1973.tb00220.x
PMID:4490008
Abstract
摘要

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Clinical application for heavy metal-complexing potential of N-acetylcysteine.N-乙酰半胱氨酸重金属络合潜力的临床应用
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The consequence of NAC on sodium arsenite-induced uterine oxidative stress.N-乙酰半胱氨酸对亚砷酸钠诱导的子宫氧化应激的影响。
Toxicol Rep. 2018 Feb 13;5:278-287. doi: 10.1016/j.toxrep.2018.02.003. eCollection 2018.
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Effects of urban coarse particles inhalation on oxidative and inflammatory parameters in the mouse lung and colon.吸入城市粗颗粒物对小鼠肺和结肠氧化和炎症参数的影响。
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A direct redox regulation of protein kinase C isoenzymes mediates oxidant-induced neuritogenesis in PC12 cells.
蛋白激酶C同工酶的直接氧化还原调节介导了PC12细胞中氧化剂诱导的神经突生长。
J Biol Chem. 2008 May 23;283(21):14430-44. doi: 10.1074/jbc.M801519200. Epub 2008 Mar 28.
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Utility of acetylcysteine in treating poisonings and adverse drug reactions.乙酰半胱氨酸在治疗中毒及药物不良反应中的应用
Drug Saf. 2000 Feb;22(2):123-48. doi: 10.2165/00002018-200022020-00005.
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N-acetylcysteine as an antidote in methylmercury poisoning.N-乙酰半胱氨酸作为甲基汞中毒的解毒剂。
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Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.硫醇试剂和Bcl-2确定了一种由甲病毒诱导的凋亡途径,该途径需要转录因子NF-κB的激活。
J Cell Biol. 1995 Dec;131(5):1149-61. doi: 10.1083/jcb.131.5.1149.
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The role of acetylcysteine in clinical toxicology.乙酰半胱氨酸在临床毒理学中的作用。
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Does N-acetylcysteine increase the excretion of trace metals (calcium, magnesium, iron, zinc and copper) when given orally?口服N-乙酰半胱氨酸会增加(钙、镁、铁、锌和铜)微量元素的排泄吗?
Eur J Clin Pharmacol. 1990;39(1):29-31. doi: 10.1007/BF02657052.