Bogdarin Iu A
Vopr Med Khim. 1979 May-Jun;25(3):274-8.
Burns of 20% of rat skin caused a decrease in content of albumins and gamma-globulins in blood and simultaneous increase in content of alpha 1- and alpha 2-globulins. Content C17 : 1 and C19 : 1 monoenoic fatty acids was decreased in blood and liver tissue of the rats with burns. These patterns were normalized after administration into the animals of synthetic anabolic steroid nerobolyl at a dose 5 mg/kg. Burning castrated male rats led to a decrease in concentration of albumins, alpha 1- and alpha 2-globulins in blood with simultaneous increase of monoenoic fatty acids in blood and liver tissue. Nerobolyl normalized these patterns at a dose 20 mg/kg, while a dose 5 mg/kg was distinctly less effective.
大鼠20%皮肤烧伤导致血液中白蛋白和γ-球蛋白含量降低，同时α1-球蛋白和α2-球蛋白含量增加。烧伤大鼠的血液和肝脏组织中C17:1和C19:1单烯脂肪酸含量降低。给动物注射5mg/kg剂量的合成同化类固醇奈洛勃林后，这些指标恢复正常。阉割雄性大鼠烧伤后，血液中白蛋白、α1-球蛋白和α2-球蛋白浓度降低，同时血液和肝脏组织中单烯脂肪酸增加。奈洛勃林以20mg/kg剂量可使这些指标恢复正常，而5mg/kg剂量的效果明显较差。
