经弗氏病毒转化的细胞集落中的红细胞生成分化
Erythropoietic differentiation in colonies of cells transformed by Friend virus.
作者信息
Singer D, Cooper M, Maniatis G M, Marks P A, Rifkind R A
出版信息
Proc Natl Acad Sci U S A. 1974 Jul;71(7):2668-70. doi: 10.1073/pnas.71.7.2668.
Abstract
Cells transformed by Friend virus in liquid suspension culture respond to low concentrations of dimethylsulfoxide by initiating hemoglobin synthesis. The kinetics of appearance of such differentiated erythroid cells is consistent with either the induction of differentiation in a uniformly susceptible population of transformed cells or selection for the growth of a distinct erythropoietic subpopulation. The dimethylsulfoxide response of individual colonies of cells transformed by Friend virus grown in semisolid medium was studied in order to distinguish between these alternatives. The data do not support a selective effect of dimethylsulfoxide on the growth of a unique erythropoietic subpopulation; they indicate, rather, that the 745A strain of cells transformed by Friend virus consists of a relatively uniform population of dimethylsulfoxide-sensitive erythropoietic cells.
摘要
在液体悬浮培养中被弗氏病毒转化的细胞，通过启动血红蛋白合成来响应低浓度的二甲基亚砜。这种分化的红系细胞出现的动力学，与在均匀易感的转化细胞群体中诱导分化，或选择生长一个独特的促红细胞生成亚群相一致。为了区分这些可能性，研究了在半固体培养基中生长的弗氏病毒转化细胞的单个集落对二甲基亚砜的反应。数据不支持二甲基亚砜对独特促红细胞生成亚群生长的选择性作用；相反，它们表明，被弗氏病毒转化的745A细胞株由相对均匀的对二甲基亚砜敏感的促红细胞生成细胞群体组成。
相似文献
1
Erythropoietic differentiation in colonies of cells transformed by Friend virus.经弗氏病毒转化的细胞集落中的红细胞生成分化
Proc Natl Acad Sci U S A. 1974 Jul;71(7):2668-70. doi: 10.1073/pnas.71.7.2668.
2
Induction of erythroid differentiation by dimethylsulfoxide in cells infected with Friend virus: relationship to the cell cycle.二甲基亚砜对感染弗氏病毒的细胞中红细胞分化的诱导作用：与细胞周期的关系
Proc Natl Acad Sci U S A. 1975 Jan;72(1):28-32. doi: 10.1073/pnas.72.1.28.
3
Dimethyl sulfoxide-induced differentiation of Friend erythroleukemia cells in the absence of cytokinesis.在无胞质分裂情况下二甲基亚砜诱导的弗氏红白血病细胞分化
Cancer Res. 1979 Oct;39(10):4058-63.
4
Induction of endogenous and of spleen focus-forming viruses during dimethylsulfoxide-induced differentiation of mouse erythroleukemia cells transformed by spleen focus-forming virus.脾脏灶形成病毒转化的小鼠红白血病细胞在二甲基亚砜诱导分化过程中内源性病毒及脾脏灶形成病毒的诱导产生
Proc Natl Acad Sci U S A. 1975 May;72(5):1863-7. doi: 10.1073/pnas.72.5.1863.
5
Inhibition of dimethyl sulfoxide-induced Friend erythroleukemia cell differentiation in vitro by lithium chloride.氯化锂对二甲基亚砜诱导的弗氏红白血病细胞体外分化的抑制作用。
Exp Cell Biol. 1985;53(5):287-93. doi: 10.1159/000163324.
6
Control of proliferation and differentiation in cells transformed by Friend virus.
Cold Spring Harb Symp Quant Biol. 1980;44 Pt 2,:1177-85. doi: 10.1101/sqb.1980.044.01.127.
7
Induction of interferon and erythropoietic differentiation in cells transformed by Friend virus.在被弗氏病毒转化的细胞中诱导干扰素及红细胞生成分化。
J Virol. 1975 Jan;17(1):27-32. doi: 10.1128/JVI.17.1.27-32.1976.
8
Cell surface charge alterations occurring during dimethylsulfoxide-induced erythrodifferentiation of Friend leukemia cells.在二甲基亚砜诱导的弗瑞德白血病细胞红系分化过程中发生的细胞表面电荷改变。
Biochem Biophys Res Commun. 1979 Feb 28;86(4):1281-7. doi: 10.1016/0006-291x(79)90255-9.
9
Interferon inhibits dimethyl sulphoxide-induced erythroid differentiation of Friend leukaemia cells.干扰素抑制二甲基亚砜诱导的弗瑞德白血病细胞的红系分化。
Nature. 1977 May 5;267(5606):50-2. doi: 10.1038/267050a0.
10
Hemoglobin synthesis in murine virus-induced leukemic cells in vitro. 3. Effects of 5-bromo-2'-deoxyuridine, dimethylformamide and dimethylsulfoxide.体外鼠病毒诱导白血病细胞中的血红蛋白合成。3. 5-溴-2'-脱氧尿苷、二甲基甲酰胺和二甲基亚砜的作用。
J Cell Physiol. 1973 Feb;81(1):63-70. doi: 10.1002/jcp.1040810108.
引用本文的文献
1
Folate depletion induces erythroid differentiation through perturbation of de novo purine synthesis.叶酸缺乏通过干扰嘌呤从头合成诱导红细胞分化。
Sci Adv. 2024 Feb 2;10(5):eadj9479. doi: 10.1126/sciadv.adj9479. Epub 2024 Jan 31.
2
FAM210B is dispensable for erythroid differentiation in adult mice.FAM210B对成年小鼠的红细胞分化并非必需。
bioRxiv. 2023 Sep 27:2023.09.26.559581. doi: 10.1101/2023.09.26.559581.
3
The immunometabolite itaconate inhibits heme synthesis and remodels cellular metabolism in erythroid precursors.免疫代谢物衣康酸抑制了红细胞前体细胞中的血红素合成并重塑了细胞代谢。
Blood Adv. 2021 Dec 14;5(23):4831-4841. doi: 10.1182/bloodadvances.2021004750.
4
Expression Silencing of Glutathione Peroxidase 4 in Mouse Erythroleukemia Cells Delays In Vitro Erythropoiesis.谷胱甘肽过氧化物酶 4 在小鼠红白血病细胞中的表达沉默可延迟体外红细胞生成。
Int J Mol Sci. 2021 Jul 21;22(15):7795. doi: 10.3390/ijms22157795.
5
The role of ORC4 in enucleation of Murine Erythroleukemia (MEL) cells is similar to that in oocyte polar body extrusion.ORC4 在去除鼠红白血病（MEL）细胞中的作用类似于在卵母细胞极体挤出中的作用。
Syst Biol Reprod Med. 2020 Dec;66(6):378-386. doi: 10.1080/19396368.2020.1822458. Epub 2020 Sep 24.
6
Murine Models of Acute Myeloid Leukaemia.急性髓系白血病的小鼠模型。
Int J Mol Sci. 2019 Jan 21;20(2):453. doi: 10.3390/ijms20020453.
7
Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility.利用遗传变异揭示转录因子结合和染色质可及性的规律。
Nat Commun. 2018 Feb 22;9(1):782. doi: 10.1038/s41467-018-03082-6.
8
A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase.孕酮受体膜成分1（PGRMC1）的新作用：亚铁螯合酶的伙伴和调节因子
Biochemistry. 2016 Sep 20;55(37):5204-17. doi: 10.1021/acs.biochem.6b00756. Epub 2016 Sep 9.
9
Identification of the Mitochondrial Heme Metabolism Complex.线粒体血红素代谢复合物的鉴定
PLoS One. 2015 Aug 19;10(8):e0135896. doi: 10.1371/journal.pone.0135896. eCollection 2015.
10
Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells.羟基脲抗性原代成人红细胞中人类胎儿珠蛋白基因的药理学诱导
Mol Cell Biol. 2015 Jul;35(14):2541-53. doi: 10.1128/MCB.00035-15. Epub 2015 May 18.
本文引用的文献
1
Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide.体外小鼠病毒诱导白血病细胞中的血红蛋白合成：二甲基亚砜对红系分化的刺激作用
Proc Natl Acad Sci U S A. 1971 Feb;68(2):378-82. doi: 10.1073/pnas.68.2.378.
2
3
Erythrocyte membrane-specific antigens in Friend virus-induced leukemia cells.弗氏病毒诱导的白血病细胞中的红细胞膜特异性抗原
Bibl Haematol. 1973;39:955-67. doi: 10.1159/000427928.
4
Early stimulation of RNA synthesis by erythropoietin in cultures of erythroid precursor cells.促红细胞生成素对红系前体细胞培养物中RNA合成的早期刺激作用。
Proc Natl Acad Sci U S A. 1973 Nov;70(11):3189-94. doi: 10.1073/pnas.70.11.3189.
5
Globin messenger-RNA induction during erythroid differentiation of cultured leukemia cells.培养的白血病细胞红系分化过程中珠蛋白信使核糖核酸的诱导
Proc Natl Acad Sci U S A. 1972 Dec;69(12):3620-3. doi: 10.1073/pnas.69.12.3620.
6
Globin messenger RNA activity in erythroid precursor cells and the effect of erythropoietin.红系前体细胞中的珠蛋白信使核糖核酸活性及促红细胞生成素的作用。
Proc Natl Acad Sci U S A. 1972 Dec;69(12):3575-9. doi: 10.1073/pnas.69.12.3575.
7
Synthesis of mouse haemoglobin and globin mRNA in leukaemic cell cultures.白血病细胞培养物中小鼠血红蛋白和珠蛋白mRNA的合成。
Nat New Biol. 1972 Oct 25;239(95):231-4. doi: 10.1038/newbio239231a0.
8
Purification of erythropoietin-responsive cells by immune hemolysis.通过免疫溶血法纯化促红细胞生成素反应性细胞。
Proc Natl Acad Sci U S A. 1972 Jun;69(6):1337-41. doi: 10.1073/pnas.69.6.1337.
9
Ultrastructural changes in Friend erythroleukemia cells treated with dimethyl sulfoxide.用二甲基亚砜处理的Friend红白血病细胞的超微结构变化
Cancer Res. 1971 Oct;31(10):1402-17.
Zotero 插件