Katz E R, Kao V
Proc Natl Acad Sci U S A. 1974 Oct;71(10):4025-6. doi: 10.1073/pnas.71.10.4025.
A mutant resistant to methanol was isolated and the mutation was shown to be located on the same linkage group with two other previously identified markers, white spore color and temperature sensitivity. In the course of analyzing methanol-resistant haploid segregants, four classes of methanol-resistant diploids were found. It is proposed that these represent mitotic recombinants, and a map of the chromosome is suggested. Segregation analysis of the diploids shows the genotypes of the diploids to be in perfect agreement with the mitotic recombination model.
分离出了一株对甲醇具有抗性的突变体,并且该突变被证明与另外两个先前鉴定出的标记——白色孢子颜色和温度敏感性——位于同一个连锁群上。在分析抗甲醇单倍体分离株的过程中,发现了四类抗甲醇二倍体。有人提出,这些代表有丝分裂重组体,并给出了一张染色体图谱。对二倍体的分离分析表明,二倍体的基因型与有丝分裂重组模型完全一致。