胸腺细胞成熟。关于可的松抗性胸腺淋巴细胞起源的研究。
Thymus cell maturation. Studies on the origin of cortisone-resistant thymic lymphocytes.
作者信息
Weissman I L
出版信息
J Exp Med. 1973 Feb 1;137(2):504-10. doi: 10.1084/jem.137.2.504.
Abstract
Outer thymic cortical large lymphocytes were labeled by transcapsular administration of tritiated thymidine. By 2-4 days after labeling, small and medium labeled lymphocyte descendants were found throughout the cortex and in the medulla. The labeled cortical lymphocytes undergo pycnosis after parenteral administration of hydrocortisone 24 h previously, but their (labeled) medullary descendants do not. In addition, parenteral administration of hydrocortisone at the time of surface labeling results in the absence of the appearance of labeled medullary descendants.
摘要
通过经胸腺囊给予氚标记胸腺嘧啶核苷来标记胸腺皮质外层的大淋巴细胞。标记后2 - 4天，在整个皮质和髓质中发现了标记的小淋巴细胞和中淋巴细胞后代。在24小时前经肠胃外给予氢化可的松后，标记的皮质淋巴细胞会发生固缩，但它们（标记的）髓质后代则不会。此外，在表面标记时经肠胃外给予氢化可的松会导致标记的髓质后代不出现。
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本文引用的文献
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