T细胞水平下红细胞之间的交叉反应。
Cross-reactions between erythrocytes at the T-cell level.
作者信息
Playfair J H, Marshall-Clarke S
出版信息
Immunology. 1973 Mar;24(3):579-88.
Abstract
The response of bone marrow (B) cells to sheep red blood cells (SRBC) was measured in the presence of thymus-derived (T) cells that had been stimulated by SRBC or RBC from other species. It was found that other RBC, notably pig and rabbit, were much more effective in stimulating T cells for a cooperative response to SRBC than would have been predicted from the very slight cross-reaction between these RBC and SRBC at the antibody level. It is concluded that recognition of antigens at the T-cell level is different, and in this case less specific, than at the level of the B cells.
摘要
在存在经绵羊红细胞（SRBC）或其他物种红细胞刺激的胸腺来源（T）细胞的情况下，测量了骨髓（B）细胞对绵羊红细胞（SRBC）的反应。结果发现，其他红细胞，尤其是猪和兔的红细胞，在刺激T细胞以协同应对SRBC方面比根据这些红细胞与SRBC在抗体水平上非常轻微的交叉反应所预测的更为有效。得出的结论是，T细胞水平对抗原的识别与B细胞水平不同，在这种情况下特异性更低。
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