Spoljar M, Eicher W, Eiermann W, Cleve H
Hum Genet. 1981;57(1):52-7. doi: 10.1007/BF00271167.
H-Y-antigen expression was analyzed in patients with transsexuality. Peripheral blood lymphocytes and various tissues were examined using the cytotoxicity assay of Goldberg et al. (1971). Peripheral blood lymphocytes from healthy male and female subjects were used as controls as well as tissues from non-transsexual individuals and from male and female C57B1/6J mice. In three female-to-male transsexuals the peripheral blood lymphocytes were H-Y antigen positive. In these patients also their ovaries, uterus, and mammae were found to be H-Y antigen positive. Three male-to-female transsexuals were examined. The peripheral blood lymphocytes in two of these patients were found to be H-Y antigen negative. Their testes were also H-Y antigen negative, as well as the epididymus, the corpus cavernosum penis, and the cremaster muscle which was analyzed in one of them. One male-to-female transsexual had peripheral blood lymphocytes which were H-Y antigen positive; this patient had testis and corpus cavernosum penis which were also H-Y-antigen positive.
对易性癖患者的H-Y抗原表达进行了分析。采用Goldberg等人（1971年）的细胞毒性试验检测外周血淋巴细胞和各种组织。来自健康男性和女性受试者的外周血淋巴细胞以及非易性癖个体和雄性及雌性C57B1/6J小鼠的组织用作对照。在三名女性变男性的易性癖患者中，外周血淋巴细胞H-Y抗原呈阳性。在这些患者中，其卵巢、子宫和乳腺也被发现H-Y抗原呈阳性。对三名男性变女性的易性癖患者进行了检查。其中两名患者的外周血淋巴细胞被发现H-Y抗原呈阴性。他们的睾丸以及附睾、阴茎海绵体和其中一名患者接受分析的提睾肌H-Y抗原也呈阴性。一名男性变女性的易性癖患者外周血淋巴细胞H-Y抗原呈阳性；该患者的睾丸和阴茎海绵体H-Y抗原也呈阳性。
