O'Connor T M, Houston L L, Samson F
Proc Natl Acad Sci U S A. 1974 Oct;71(10):4198-202. doi: 10.1073/pnas.71.10.4198.
Neuronal microtubules in a variety of nerve cell types are unaffected by high hydrostatic pressures over a range of 1400-10,000 pounds/inch(2) and periods of 10-45 min. Similarly, purified tubulin polymerized to form microtubules in vitro were not depolymerized by the same range of pressures. The depolymerization of microtubules in several types of non-neuronal cells, which has been reported, may have been over-generalized with regard to the direct action of pressure on microtubule stability.
多种神经细胞类型中的神经元微管，在1400 - 10000磅/平方英寸的高静水压力范围以及10 - 45分钟的时间段内不受影响。同样，体外聚合形成微管的纯化微管蛋白在相同压力范围内也不会解聚。已报道的几种非神经元细胞类型中微管的解聚，可能在压力对微管稳定性的直接作用方面被过度概括了。
