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T细胞在实验性肾盂肾炎中的作用。

The role of the T cell in experimental pyelonephritis.

作者信息

Coles G A, Chick S, Hopkins M, Ling R, Radford N J

出版信息

Clin Exp Immunol. 1974 Apr;16(4):629-36.

Abstract

The role of the thymus-dependent (T) cell in experimental pyelonephritis has been studied using neonatally thymectomized or ALG-treated rats. The number of kidney scars and the macroscopic or microscopic appearance of the lesions were unaffected by the presence or absence of T cells. Responses to both the O and K antigens of appear to be T cell-independent in the rat.

摘要

利用新生期胸腺切除或经抗淋巴细胞球蛋白(ALG)处理的大鼠,对胸腺依赖性(T)细胞在实验性肾盂肾炎中的作用进行了研究。肾瘢痕的数量以及病变的大体或显微镜下表现不受T细胞存在与否的影响。在大鼠中,对[某种细菌]O抗原和K抗原的反应似乎不依赖于T细胞。 (注:原文中“appear to be T cell-independent in the rat.”前的“both the O and K antigens of ”这里少了具体指代的细菌等相关内容,翻译时补充了[某种细菌]以便语句通顺完整)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e51/1554006/062891248bf7/clinexpimmunol00277-0123-a.jpg

本文引用的文献

2
SERUM-ANTIBODY LEVELS AS AN INDICATION OF CLINICALLY INAPPARENT PYELONEPHRITIS.
Lancet. 1964 Nov 14;2(7368):1027-33. doi: 10.1016/s0140-6736(64)90988-2.
3
Distribution of antigens reactive with rabbit antirat thymic cell serum.
Transplantation. 1971 Apr;11(4):412-4. doi: 10.1097/00007890-197104000-00010.
7
Serum antibody response in renal versus bladder bacteriuria.
J Infect Dis. 1971 May;123(5):539-43. doi: 10.1093/infdis/123.5.539.

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