雄性小鼠颌下腺提取物对小鼠体内斑块形成细胞的免疫抑制作用：睾丸切除可消除该作用。
Immunosuppressive effect of male mouse submandibular gland extracts on plaque-forming cells in mice: abolition by orchiectomy.
作者信息
Kongshavn P A, Lapp W S
出版信息
Immunology. 1972 Feb;22(2):227-30.
Abstract
The plaque-forming response to sheep red blood cells is suppressed in mice treated with crude saline extracts of normal male mouse submandibular glands. Extracts from adult male mice orchiectomized at 2 weeks of age are ineffective, suggesting that the presence of this suppressive substance in the male mouse submandibular gland is testosterone-dependent.
摘要
用正常雄性小鼠下颌下腺的粗盐水提取物处理的小鼠，对绵羊红细胞的噬斑形成反应受到抑制。对2周龄时进行睾丸切除的成年雄性小鼠的提取物无效，这表明雄性小鼠下颌下腺中这种抑制性物质的存在依赖于睾酮。
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本文引用的文献
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PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM.从小鼠唾液腺中纯化一种神经生长促进蛋白及其神经细胞毒性抗血清。
Proc Natl Acad Sci U S A. 1960 Mar;46(3):302-11. doi: 10.1073/pnas.46.3.302.
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Atrophy of the lymphoid tissues of mice induced by extracts of the submaxillary gland.
Proc Soc Exp Biol Med. 1967 Oct;126(1):212-6. doi: 10.3181/00379727-126-32404.
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Inhibitory action of submaxillary gland on thymus and lymphoid tissues of the mouse.
Am J Physiol. 1968 Dec;215(6):1337-42. doi: 10.1152/ajplegacy.1968.215.6.1337.
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Further improvements in the plaque technique for detecting single antibody-forming cells.用于检测单个抗体形成细胞的蚀斑技术的进一步改进。
Immunology. 1968 Apr;14(4):599-600.
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Effect of mouse submandibular gland extracts on survival of H-2 incompatible skin allografts.小鼠颌下腺提取物对H-2不相容皮肤同种异体移植物存活的影响。
Immunology. 1970 Aug;19(2):363-7.
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Sex differences in survival of H-2 incompatible skin grafts in mice treated with antithymocyte serum.
Nature. 1970 May 2;226(5244):451. doi: 10.1038/226451a0.
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