Woodruff R K, Malpas J S, White F E
Cancer. 1979 Jun;43(6):2344-7. doi: 10.1002/1097-0142(197906)43:6<2344::aid-cncr2820430626>3.0.co;2-7.
The clinical features and the results of treatment of twelve patients with solitary plasmacytoma of bone (SPB) are reported. The median age at presentation was 53 years and there was a predominance of males. Five patients have developed multiple myeloma (MM), for within three years and one after twelve years. Seven patients have not shown evidence of dissemination, and five are alive 1--15 years (median 9 years) after diagnosis. Two patients had metastases to local lymph nodes. There are no reliable criteria by which patients with truly SPB can be prospectively distinguished from those with occult MM, and it is recommended that all patients with apparent SPB should receive "curative" local therapy.
报告了12例骨孤立性浆细胞瘤（SPB）患者的临床特征及治疗结果。发病时的中位年龄为53岁，男性居多。5例患者在3年内发展为多发性骨髓瘤（MM），1例在12年后发展为MM。7例患者未出现播散迹象，5例在诊断后存活1至15年（中位9年）。2例患者出现局部淋巴结转移。目前尚无可靠标准可前瞻性地区分真正的SPB患者与隐匿性MM患者，建议所有明显为SPB的患者均应接受“根治性”局部治疗。
