城市和农村社区健康成人及儿童肠道大肠菌群中的抗生素耐药性及可传递R因子
Antibiotic resistance and transmissible R-factors in the intestinal coliform flora of healthy adults and children in an urban and a rural community.
作者信息
Linton K B, Lee P A, Richmond M H, Gillespie W A, Rowland A J, Baker V N
出版信息
J Hyg (Lond). 1972 Mar;70(1):99-104. doi: 10.1017/s0022172400022130.
Faeces of healthy adults and of children under the age of 5, none of whom were attending hospital or receiving antibiotics, were examined for the presence of antibiotic resistant coliform bacilli.A higher proportion of children (67%) than of adults (46%) carried resistant strains and this difference was observed in both the rural and urban groups.Rural members of both age groups more often carried resistant organisms than urban members. Among rural adults, the incidence of drug-resistant strains was 63% in those whose occupation involved close contact with farm animals, compared with 29% in those with other occupations. The survey took place before the implementation of the Swann Report could have influenced the use of antibiotics in animal foodstuffs.Transmissible R-factors were demonstrated in 61% of the resistant strains. The incidence of transmissible resistance was similar among adults and children in town and country.
对健康成年人以及5岁以下儿童的粪便进行了检查，以确定其中是否存在耐抗生素大肠埃希氏菌。这些人都未住院或接受抗生素治疗。携带耐药菌株的儿童比例（67%）高于成年人（46%），农村和城市人群中均观察到了这种差异。两个年龄组的农村居民比城市居民更常携带耐药菌。在农村成年人中，职业与农场动物密切接触者的耐药菌株发生率为63%，而从事其他职业者为29%。该调查在斯旺报告实施之前进行，当时该报告不可能对动物食品中抗生素的使用产生影响。在61%的耐药菌株中发现了可传递的R因子。城乡成年人和儿童中可传递耐药性的发生率相似。
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