Moe H
Cell Tissue Res. 1979 Apr 12;197(3):443-51. doi: 10.1007/BF00233569.
The migration of the ameloblasts in the continuously erupting incisors of the rat is accompanied by cell loss. Ameloblasts degenerate near the mesial and lateral cemento-enamel junctions in the secretory zone and in the middle two thirds of the region of postsecretory transition, degeneration being most marked where these areas merge. These findings support the hypothesis that the prism decussation in the enamel results from alternating transverse rows of secretory ameloblasts sliding past each other whilst elaborating their rods. The distribution of the degenerating cells suggests, however, that the sliding cell rows are not exactly transverse but arcuate, with the opening facing incisally. The progress of structural alterations of the nuclei in the degenerating ameloblasts appears to follow the pattern earlier described in vinblastine-damaged ameloblasts.
在大鼠不断萌出的切牙中，成釉细胞的迁移伴随着细胞丢失。成釉细胞在分泌区的近中及远中牙骨质-釉质界附近以及分泌后过渡区中间三分之二区域发生退变，在这些区域合并处退变最为明显。这些发现支持以下假说：釉质中的棱柱交叉是由于分泌性成釉细胞的交替横向排彼此滑动，同时形成釉柱所致。然而，退变细胞的分布表明，滑动的细胞排并非完全横向，而是呈弧形，开口朝向切端。退变成釉细胞核结构改变的进展似乎遵循先前在长春花碱损伤的成釉细胞中描述的模式。
